ArticleJournal of the American Heart Association2023
Heart Rate Variability Parameter Changes in Patients With Acute Ischemic Stroke Undergoing Intravenous Thrombolysis.
Article in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Impact of coexisting obesity and malnutrition on the clinical outcomes of acute ischemic stroke patients treated with intravenous thrombolysis: a cohort-based study.Frontiers in nutrition · 2026Article
- Heart Rate Variability Dynamics as Predictors of Functional Recovery and Mortality After Acute Ischemic Stroke.Biomedicines · 2025Article
- Heart Rate Variability and Autonomic Dysfunction After Stroke: Prognostic Markers for Recovery.Biomedicines · 2025Review
- Article
- The Roles of Heart Rate Variability in Cerebral Stroke.Neuropsychiatric disease and treatment · 2025Review
- A nomogram predictive model for factors influencing prognosis of acute ischemic stroke patients after intravenous thrombolysis.American journal of translational research · 2025Article
- Early heart rate predicts 3-month outcomes in acute ischemic stroke patients receiving intravenous thrombolysis: a machine learning approach.Frontiers in neurology · 2025Article
- Comprehensive autonomic nervous system evaluation in stroke patients: heart rate variability as a cornerstone for recovery prediction.Frontiers in neurology · 2025Review
- Beat-to-Beat Blood Pressure Variability Within 24 Hours of Ischemic Stroke Onset: A Potential Predictor of Functional Prognosis.Journal of the American Heart Association · 2024Article
- SDNN predicts 90-day disability after intravenous thrombolysis: autonomic dysfunction as a novel predictors in acute ischemic stroke.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Autonomic dysfunction has been revealed in patients with acute ischemic stroke and is associated with poor prognosis. However, autonomic nervous system function assessed by heart rate variability (HRV) and its relationship with clinical outcomes in patients undergoing intravenous thrombolysis (IVT) remain unknown. Methods and Results Patients who did and did not undergo IVT between September 2016 and August 2021 were prospectively and consecutively recruited. HRV values were measured at 1 to 3 and 7 to 10 days after stroke to assess autonomic nervous system function. A modified Rankin scale score ≥2 at 90 days was defined as an unfavorable outcome. Finally, the analysis included 466 patients; 224 underwent IVT (48.1%), and 242 did not (51.9%). Linear regression showed a positive correlation of IVT with parasympathetic activation-related HRV parameters at 1 to 3 days (high frequency:
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