Evidence map›Paper›PMID 37231888›Full record

ArticleDigestive diseases (Basel, Switzerland)2023

Safety of Cold Snare Polypectomy during Continuous Use of Antithrombotic Drugs for Delayed Post-Polypectomy Bleeding: A Pilot Study.

Junnosuke Hayasaka, Satoshi Yamashita, Akira Matsui, Yusuke Kawai, Yorinari Ochiai, Takayuki Okamura, Yugo Suzuki, Yutaka Mitsunaga, Kosuke Nomura, Masami Tanaka and 5 more

Open access · greenAbstract read
In one paragraph

Article in Digestive diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Junnosuke HayasakaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Satoshi YamashitaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Akira MatsuiDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Yusuke KawaiDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Yorinari OchiaiDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Takayuki OkamuraDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Yugo SuzukiDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Yutaka MitsunagaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Kosuke NomuraDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Masami TanakaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Kazuhiro FuchinoueDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Hiroyuki OdagiriDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Daisuke KikuchiDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Yutaka TakazawaDepartment of Pathology, Toranomon Hospital, Tokyo, Japan.
Shu HoteyaDepartment of Gastroenterology, Toranomon Hospital, Tokyo, Japan.
Toranomon Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCold snare polypectomy is a high-risk endoscopic procedure with a low delayed post-polypectomy bleeding rate. However, it is unclear whether delayed post-polypectomy bleeding rates increase during continuous antithrombotic treatment. This study aimed to determine the safety of cold snare polypectomy during continuous antithrombotic treatment.

methodsThis single-center, retrospective cohort study enrolled patients who underwent cold snare polypectomy during antithrombotic treatment between January 2015 and December 2021. Patients were divided into continuation and withdrawal groups based on whether they continued with antithrombotic drugs or not. Propensity score matching was performed using age, sex, Charlson comorbidity index, hospitalization, scheduled treatment, type of antithrombotic drugs used, multiple medications used, indication for antithrombotic drugs, and gastrointestinal endoscopist qualifications. The delayed polypectomy bleeding rates were compared between the groups. Delayed polypectomy bleeding was defined as the presence of blood in stools and requiring endoscopic treatment or a decrease in hemoglobin level by 2 g/dL or more.

resultsThe continuation and withdrawal groups included 134 and 294 patients, respectively. Delayed polypectomy bleeding was observed in 2 patients (1.5%) and 1 patient (0.3%) in the continuation and withdrawal groups, respectively (p = 0.23), before propensity score matching, with no significant difference. After propensity score matching, delayed polypectomy bleeding was observed in 1 patient (0.9%) in the continuation group but not in the withdrawal group, with no significant difference.

conclusionCold snare polypectomy during continuous antithrombotic treatment did not significantly increase delayed post-polypectomy bleeding rates. Therefore, this procedure may be safe during continuous antithrombotic treatment.

Indexed as

Colonic PolypsColonoscopyFibrinolytic AgentsHemorrhageHumansPilot ProjectsRetrospective StudiesFibrinolytic AgentsAntithrombotic drugCold snare polypectomyColonoscopyColon polypDelayed post-polypectomy bleeding

Identifiers

PMID37231888
PMCPMC10614267
OpenAlexW4378347459

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.