ArticleEuropean stroke journal2023
Early post-endovascular treatment contrast extravasation on dual-energy CT is associated with clinical and radiological stroke outcomes: A 10-year single-centre experience.
Article in European stroke journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of dual-energy CT in distinguishing intracerebral hemorrhage from contrast staining: a systematic review and meta-analysis with radiation dose assessment.La Radiologia medica · 2026Pooled it
- Differentiating Hemorrhage and Contrast Extravasation After Mechanical Thrombectomy Using Virtual Non-Contrast Photon-Counting CT.Clinical neuroradiology · 2026Article
- Impact of Preprocedural Collateral Status on Hemorrhagic Transformation and Outcomes After Endovascular Thrombectomy in Acute Ischemic Stroke.Diagnostics (Basel, Switzerland) · 2025Article
- Differential impact of deep intraparenchymal hyperdensities versus subarachnoid/cortical hyperdensities on futile reperfusion after mechanical thrombectomy: a propensity score-matched study.Frontiers in neurology · 2025Article
- Machine learning, clinical-radiomics approach with HIM for hemorrhagic transformation prediction after thrombectomy and treatment.Frontiers in neurology · 2025Article
- Procedural Blood Pressure and Intracranial Hemorrhage on Dual-Energy Computed Tomography After Endovascular Stroke Treatment.Cardiovascular and interventional radiology · 2024Article
- Clinical Applications of Dual-Energy Computed Tomography for Acute Ischemic Stroke.Stroke (Hoboken, N.J.) · 2024Review
- Determinants and Clinical Relevance of Iodine Contrast Extravasation after Endovascular Thrombectomy: A Dual-Energy CT Study.AJNR. American journal of neuroradiology · 2023Article
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6 authors.
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Abstract
objectiveTo determine the association between early post-endovascular treatment (EVT) contrast extravasation (CE) on dual-energy CT (DECT) and stroke outcomes.
methodsEVT records in 2010-2019 were screened. Exclusion criteria included the occurrence of immediate post-procedural intracranial haemorrhage (ICH). Hyperdense areas on iodine overlay maps were scored according to the Alberta Stroke Programme Early CT Score (ASPECTS), thus forming a CE-ASPECTS. Maximum parenchymal iodine concentration and maximum iodine concentration relative to the torcula were recorded. Follow-up imaging was reviewed for ICH. The primary outcome measure was the modified Rankin Scale (mRS) at 90 days.
resultsOut of 651 records, 402 patients were included. CE was found in 318 patients (79%). Thirty-five patients developed ICH on follow-up imaging. Fourteen ICHs were symptomatic. Stroke progression occurred in 59 patients. Multivariable regression showed a significant association between decreasing CE-ASPECTS and the mRS at 90 days (adjusted (a)cOR: 1.10, 95% CI: 1.03-1.18), NIHSS at 24-48 h (aβ: 0.57, 95% CI: 0.29-0.84), stroke progression (aOR: 1.14, 95% CI: 1.03-1.26) and ICH (aOR: 1.21, 95% CI: 1.06-1.39), but not symptomatic ICH (aOR 1.19, 95% CI: 0.95-1.38). Iodine concentration was significantly associated with the mRS (acOR: 1.18, 95% CI: 1.06-1.32), NIHSS (aβ: 0.68, 95% CI: 0.30-1.06), ICH (aOR: 1.37, 95% CI: 1.04-1.81) and symptomatic ICH (aOR: 1.19, 95% CI: 1.02-1.38), but not stroke progression (aOR: 0.99, 95% CI: 0.86-1.15). Results of the analyses with relative iodine concentration were similar and did not improve prediction.
conclusionsCE-ASPECTS and iodine concentration are both associated with short- and long-term stroke outcomes. CE-ASPECTS is likely a better predictor for stroke progression.
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