Evidence map›Paper›PMID 37231611›Full record

ArticleAnnals of clinical and translational neurology2023

Pulvinar neuromodulation for seizure monitoring and network modulation in temporal plus epilepsy.

Yash Shashank Vakilna, Ganne Chaitanya, Muhammad Ubaid Hafeez, Adeel Ilyas, Manojkumar Saranathan, Jay Gavvala, Nitin Tandon, Sandipan Pati

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of clinical and translational neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Neurostimulation in children with drug-resistant epilepsy: strategies in subcortical targeting and systematic review of the evidence.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Pooled it
  2. Article
  3. Medial Pulvinar Nucleus as a Causal Hub for Heteromodal Naming.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Seizure Detection and Lateralization Using Thalamic Deep Brain Stimulator Recordings.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yash Shashank VakilnaTexas Comprehensive Epilepsy Program, Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Ganne ChaitanyaTexas Comprehensive Epilepsy Program, Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Muhammad Ubaid HafeezTexas Comprehensive Epilepsy Program, Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Adeel IlyasDepartment of Neurosurgery, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-5545-4398
Manojkumar SaranathanDepartment of Radiology, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Jay GavvalaTexas Comprehensive Epilepsy Program, Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Nitin TandonTexas Comprehensive Epilepsy Program, Department of Neurosurgery, The University of Texas Health Science Center at Houston, Houston, Texas, USA.
Sandipan PatiTexas Comprehensive Epilepsy Program, Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, USA.ORCID 0000-0003-4171-2138
The University of Texas Health Science Center at Houston · USShared Spectrum Company (United States) · USUniversity of Alabama at Birmingham · USUniversity of Massachusetts Chan Medical School · US

Funding

Network based neuro-modulation for mesial temporal lobe epilepsyUH3NS119834 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI AAZHANG, BEHNAAM, BANKIM BEHARI PATI, SANDIPAN PATI · 2022 to 2024
$2.2M
6 · The paper itself

Abstract

Deep brain stimulation (DBS) is a promising treatment for drug-refractory epilepsies (DRE) when targeting the anterior nuclei of thalamus (ANT). However, targeting other thalamic nuclei, such as the pulvinar, shows therapeutic promise. Our pioneering case study presents the application of ambulatory seizure monitoring using spectral fingerprinting (12.15-17.15 Hz) recorded through Medtronic Percept DBS implanted bilaterally in the medial pulvinar thalami. This technology offers unprecedented opportunities for real-time monitoring of seizure burden and thalamocortical network modulation for effective seizure reduction in patients with bilateral mesial temporal and temporal plus epilepsies that are not suitable for resection.

Indexed as

Deep Brain StimulationEpilepsyPulvinarElectrodes, ImplantedHumansSeizures

Identifiers

PMID37231611
PMCPMC10351657
OpenAlexW4378349465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.