ArticleBMC women's health2023
Associations of LH and FSH with reproductive hormones depending on each stage of the menopausal transition.
Article in BMC women's health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Beyond Estrogen: Distribution and Hormonal Correlates of Serum Testosterone Among Postmenopausal U.S. Women, NHANES 2011-2016 and 2021-2023.Journal of clinical medicine · 2026Article
- Pharmacokinetic analysis of 25 mg estradiol subcutaneous bioabsorbable implant in postmenopausal women (CLARA STUDY).Menopause (New York, N.Y.) · 2026Article
- Clinical factors influencing serum CA125 levels and their implications for diagnosing ovarian tumors.Bioinformation · 2026Article
- Gonadotropin trajectories among postmenopausal women not using hormone therapy.Menopause (New York, N.Y.) · 2026Article
- Sex hormone-psoriasis interactions: from sex-specific clinical features to immunoregulatory mechanisms.Frontiers in immunology · 2026Review
- Kisspeptin-10 Ameliorates Obesity-Diabetes with Diverse Effects on Ileal Enteroendocrine Cells and Pancreatic Islet Morphology in High-Fat Fed Female Mice.Biomolecules · 2025Article
- Preparation and Immunogenicity Evaluation of a Ferritin-Based GnRH Nanoparticle Vaccine.Vaccines · 2025Article
- Article
- Biochemistry of perimenopause and menopause - in-depth study on midlife crisis among rural women in Bengal.Journal of family medicine and primary care · 2025Article
- Unraveling the Clinical FSH Conundrum: Insights From the Small Ovarian Reserve Heifer Model.Molecular reproduction and development · 2025Review
- Article
- Effectiveness and safety of hormone replacement therapy in the treatment of menopausal syndrome: a meta-analysis.American journal of translational research · 2025Review
- Oviduct Glycoprotein 1 (OVGP1) Diagnoses Polycystic Ovary Syndrome (PCOS) Based on Machine Learning Algorithms.ACS omega · 2024Article
- An Array SPRi Biosensor for the Determination of Follicle-Stimulating Hormone in Blood Plasma.Sensors (Basel, Switzerland) · 2023Article
- Management of Obesity in Menopausal Women: Implications for Metabolic Health and Minimally Invasive Surgery.Gynecology and minimally invasive therapyReview
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAssociations of luteinizing hormone (LH) with androgens during the menopausal transition and associations between follicle-stimulating hormone (FSH) levels and various diseases related to reproductive hormones in postmenopause have received much attention. LH and FSH are also known to be associated with activities of enzymes related to reproductive hormones. We examined the associations of LH and FSH with androgens and estrogens in each stage of the menopausal transition according to a classification from menopausal transition to postmenopause.
methodsThis study was a cross-sectional design. We basically used the Stage of Reproductive Aging Workshop (STRAW) + 10. We divided the 173 subjects into 6 groups according to menstrual regularity and follicle-stimulating hormone level: mid reproductive stage (Group A), late reproductive stage (Group B), early menopausal transition (Group C), late menopausal transition (Group D), very early postmenopause (Group E) and early postmenopause (Group F). Levels of LH, FSH, dehydroepiandrosterone sulfate (DHEAS), estradiol, estrone, testosterone (T), free T, androstenedione and androstenediol were measured.
resultsIn Group A, LH showed significant positive correlations with androstenedione and estrone. In Group D, LH was positively associated with T and free T and was negatively associated with estradiol. In Groups B, C, D and F, LH showed significant positive correlations with FSH, and there was a tendency for an association between LH and FSH in Group E. FSH was associated with estradiol but not with estrone in Groups C and D.
conclusionThe associations of LH and FSH with reproductive hormones are different depending on the stage of the menopausal transition.
trial registrationTrial registration number 2356-1; Date of registration: 18/02/2018, retrospectively registered.
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