ReviewNature reviews. Cardiology2023
Global epidemiology of acute coronary syndromes.
Review in Nature reviews. Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
89 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy and safety of colchicine in patients with acute coronary syndrome: a systematic review and meta-analysis of randomized controlled trials.BMC cardiovascular disorders · 2025Pooled it
- Platelet-To-Lymphocyte Ratio Efficiency in Predicting Major Adverse Cardiovascular Events After Percutaneous Coronary Intervention in Acute Coronary Syndromes: A Meta-Analysis.Reviews in cardiovascular medicine · 2025Pooled it
- Immuno-resolving nitric oxide-generating stents for coordinated vascular healing.Bioactive materials · 2027Article
- Integrating Clinical Evidence with PBPK Modeling to Assess PPI-Clopidogrel-CYP2C19 Interactions in Chinese ACS Patients.Pharmaceutical research · 2026Observational
- Myocardial infarction and lung cancer research from 1995 to 2026: a WoSCC- and PubMed-based bibliometric analysis.Journal of thoracic disease · 2026Article
- Ischemic Heart Disease in the Middle East and North Africa, 1990-2021: An Integrated Analysis of Temporal Trends, Country-Level Variation, SDI Patterns, and Risk Factors.Health science reports · 2026Article
- Optimal time for aspirin withdrawal after PCI in ACS: a pairwise and network meta-analysis with time to event data of randomized trials.Cardiovascular intervention and therapeutics · 2026Review
- Overview of methodology and characteristics of national acute coronary syndrome registries in high-income countries: a scoping review.European heart journal open · 2026Review
- Impact of residual cholesterol and inflammation risk on non-culprit plaque progression in patients with acute coronary syndrome: a serial optical coherence tomography study.BMC cardiovascular disorders · 2026Article
- Article
- Advances in the Diagnosis and Management of Acute Coronary Syndrome: A Clinical Review.Cureus · 2026Review
- TREAT-Netv2: regional wall motion-informed video-tabular fusion for ACS treatment prediction.International journal of computer assisted radiology and surgery · 2026Article
- Stress hyperglycemia ratio improves 28-day mortality prediction beyond GRACE score in critically ill patients with acute coronary syndrome: a retrospective cohort study from MIMIC-IV.BMC cardiovascular disorders · 2026Article
- Scalable regionalised quality improvement model for ACS management in resource-limited primary healthcare facilities.Journal of epidemiology and community health · 2026Article
- The Evolution of the Mental Health-Acute Coronary Syndrome Intersection: A 50-Year Bibliometric Mapping and Changepoint Analysis (1975-2025).Healthcare (Basel, Switzerland) · 2026Article
- RNA biomarker signatures for prediction of acute kidney injury in acute coronary syndrome patients undergoing PCI.BMC nephrology · 2026Observational
- Association of Coronary Sinus Flow with Long-Term Risk of Acute Coronary Syndrome and Composite Cardiovascular Events.Biomedicines · 2026Article
- Digital Cognitive Behavioral Therapy for Cardiac Anxiety After Myocardial Infarction: Effects on Disease-Specific Health Status-Detailed Methods and Protocol.JACC. Advances · 2026Article
- Association of low body mass index with the risk of major adverse cardiovascular events among patients with acute myocardial infarction: a single-center cohort study from Iran.BMC cardiovascular disorders · 2026Article
- Redefining Dual Antiplatelet Strategies After Acute Coronary Syndrome: Insights from Recent RCTs.Journal of clinical medicine · 2026Review
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This Review provides an epidemiological overview of global mortality from acute coronary syndromes (ACS). Across the regions of the world where data are available, mortality from ACS - including premature (age <70 years) mortality from ACS - was higher in men than in women. In both sexes, age-standardized mortality rates (ASMRs) for ACS in 2020 were highest in lower-income global regions. However, 20 years earlier, ASMRs for ACS were highest in higher-income global regions, including Europe, Northern America and Oceania. These higher-income regions have seen progressive reductions in mortality from ACS during the past 20 years, which is in contrast to the more stable levels of mortality from ACS in Asia and in Latin America and the Caribbean. In the seven African countries with data available, a small upwards trend in ASMRs for ACS was observed, reflecting an epidemiological transition that is already well advanced in these regions. Consistent with these changes during the past 20 years were >50% reductions in ASMRs for ACS in the high-income countries of the world compared with <15% reductions in lower-middle-income countries. Policymakers need more complete epidemiological data across and within global regions to identify those countries in which the burden of death from ACS is greatest and the need to implement preventive strategies is most pressing.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.