ArticleNature communications2023
Detailed mapping of Bifidobacterium strain transmission from mother to infant via a dual culture-based and metagenomic approach.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mother-to-infant vertical transmission in early life: a systematic review and proportional meta-analysis of Bifidobacterium strain transmissibility.NPJ biofilms and microbiomes · 2025Pooled it
- Genetic and enzymatic basis of xylooligosaccharide metabolism byGut microbes · 2026Article
- Gut microbial metabolism of peanuts generates immunoregulatory metabolites.Gut microbes · 2026Article
- Metabolic pathway analysis reveals hierarchical pentose sugar utilization and metabolic flexibility ofGut microbes · 2026Article
- Bifidobacteria: biogeography, host adaptation and ecological functions.Nature reviews. Microbiology · 2026Review
- Strain transmission links human microbiomes along the oral-gut axis and across cohabiting individuals.Cell press blue · 2026Article
- Novel insights into how gestational diet affects maternal-infant microbiota: a cross-sectional causal mediation analysis at one month postpartum.European journal of nutrition · 2026Observational
- Article
- Metagenomic strain tracking reveals patterns of bacterial spread and the impact of water chlorination.medRxiv : the preprint server for health sciences · 2026Article
- High-throughput single-cell isolation ofMicrobiology spectrum · 2026Article
- Molecular Relatedness of Maternal and Neonatal Multidrug-Resistant Gram-Negative Colonization Isolates in Low- and Middle-Income Countries: A Systematic Review.Open forum infectious diseases · 2026Review
- Review
- Significant strain microdiversity in mother-infant dyad cohorts across ethnic groups reveals population specificity of bifidobacteria microbiota transmission.Frontiers in microbiology · 2026Article
- Structural variation analysis suggests strain-level maternal-infant microbial transmission in early life.Frontiers in cellular and infection microbiology · 2026Article
- The analysis of bidirectional long short-term memory network model for construction of cultural gene map and information extraction.Scientific reports · 2025Article
- Breastfeeding and the milk resistome shape the establishment and transmission of antibiotic resistance genes in the infant gut microbiome.Gut microbes · 2025Article
- Exclusive breastfeeding is associated with the gut microbiome maturation in infants according to delivery mode.Gut microbes · 2025Article
- Early life gut microbiome and its impact on childhood health and chronic conditions.Gut microbes · 2025Review
- Assembly of the infant gut microbiome and resistome are linked to bacterial strains in mother's milk.Nature communications · 2025Article
- Early-life gut and oral microbiota development: a multi-niche study including mother-partner-infant triads.BMC microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A significant proportion of the infant gut microbiome is considered to be acquired from the mother during and after birth. Thus begins a lifelong and dynamic relationship with microbes that has an enduring impact on host health. Based on a cohort of 135 mother-infant (F = 72, M = 63) dyads (MicrobeMom: ISRCTN53023014), we investigated the phenomenon of microbial strain transfer, with a particular emphasis on the use of a combined metagenomic-culture-based approach to determine the frequency of strain transfer involving members of the genus Bifidobacterium, including species/strains present at low relative abundance. From the isolation and genome sequencing of over 449 bifidobacterial strains, we validate and augment metagenomics-based evidence to reveal strain transfer in almost 50% of dyads. Factors important in strain transfer include vaginal birth, spontaneous rupture of amniotic membranes, and avoidance of intrapartum antibiotics. Importantly, we reveal that several transfer events are uniquely detected employing either cultivation or metagenomic sequencing, highlighting the requirement for a dual approach to obtain an in-depth insight into this transfer process.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.