ArticlePreventing chronic disease2023
Determinants of Adherence to Antihypertension Medications Among Patients at a Tertiary Care Hospital in Islamabad, Pakistan, 2019.
Article in Preventing chronic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Effectiveness of a Behavior Change Wheel-Informed WeChat-Based Messaging Intervention to Improve Medication Adherence After Percutaneous Coronary Intervention: 12-Week Quasi-Experimental Study.Journal of medical Internet research · 2026Article
- Prevalence and Determinants of Uncontrolled Hypertension Among Treated Adults in a Rural Primary Health Care Facility in South Africa: A Cross-Sectional Study.Epidemiologia (Basel, Switzerland) · 2026Article
- The predictors of treatment adherence among hypertensive patients with cost-free access.Scientific reports · 2026Article
- Health Systems and Self-Reported Medication Adherence in Patients with Hypertension: A cross-sectional comparison of Jamaica and Colombia.Research square · 2025Article
- Understanding Treatment Adherence in Chronic Diseases: Challenges, Consequences, and Strategies for Improvement.Journal of clinical medicine · 2025Review
- Impact of hypertension knowledge on adherence to antihypertensive therapy: a cross-sectional study in primary health care centers during the 2024 Sudan conflict.BMC primary care · 2025Article
- Article
- A cross-sectional study on the assessment of adherence to cardiovascular medications in Sudan heart center.PloS one · 2025Article
- Self-Monitoring of Blood Pressure in Yemen: Preliminary Insights Into Knowledge, Attitudes and Practices of Hypertensive Patients.Vascular health and risk management · 2025Article
- The Relationship Between Intolerance of Uncertainty and Treatment Adherence: The Moderating Effect of Self-Compassion on the Chain Mediation Model.Patient preference and adherence · 2025Article
- Article
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6 authors.
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Abstract
introductionMedication nonadherence leads to poor health outcomes, frequent complications, and high economic impact. Our objective was to assess the determinants of adherence to medication regimens among patients with hypertension.
methodsWe conducted a cross-sectional study of patients with hypertension attending the cardiology clinic of a tertiary care hospital in Islamabad, Pakistan. Data were collected by using semistructured questionnaires. A score of 7 or 8 on the 8-item Morisky Medication Adherence Scale was classified as good adherence, 6 as moderate, and less than 6 as nonadherence. Logistic regression was performed to determine covariates associated with medication adherence.
resultsWe enrolled 450 patients with hypertension (mean age, 54.5 y; SD, 10.6). Medication adherence was good among 115 (25.6%) patients and moderate among 165 (36.7%); 170 (37.8%) patients were nonadherent. Most patients (72.7%) had uncontrolled hypertension. Nearly half (49.6%) were unable to afford monthly medication. In bivariate analysis, nonadherence was associated with female sex (odds ratio [OR], 1.44; P = .003) and long waiting times in the health care facility (OR, 2.93; P = .005); the presence of comorbidities (OR, 0.62; P = .01) was associated with good adherence. In multivariate analysis, nonadherence was associated with unaffordability of treatment (OR, 2.25; P = .002) and uncontrolled hypertension (OR, 3.16; P < .001). Good adherence determinants included adequate counseling (OR, 0.29; P < .001) and education (OR, 0.61; P = .02).
conclusionAddressing identified barriers, including medication affordability and patient counseling, should be included in Pakistan's national policy on noncommunicable disease.
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