Evidence map›Paper›PMID 37229536›Full record

ArticleAdvanced healthcare materials2023

A Laser-Driven Microrobot for Thermal Stimulation of Single Cells.

Philipp Harder, Nergishan İyisan, Chen Wang, Fabian Kohler, Irina Neb, Harald Lahm, Martina Dreßen, Markus Krane, Hendrik Dietz, Berna Özkale

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Application of micro/nanorobot in medicine.Frontiers in bioengineering and biotechnology · 2024
    Review
  8. Medical Imaging Technology for Micro/Nanorobots.Nanomaterials (Basel, Switzerland) · 2023
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Philipp HarderMicrorobotic Bioengineering Lab (MRBL), School of Computation Information and Technology, Technical University of Munich, Hans-Piloty-Straße 1, 85748, Garching, Germany.
Nergishan İyisanMicrorobotic Bioengineering Lab (MRBL), School of Computation Information and Technology, Technical University of Munich, Hans-Piloty-Straße 1, 85748, Garching, Germany.
Chen WangMicrorobotic Bioengineering Lab (MRBL), School of Computation Information and Technology, Technical University of Munich, Hans-Piloty-Straße 1, 85748, Garching, Germany.
Fabian KohlerMunich Institute of Biomedical Engineering, Technical University of Munich, Boltzmannstraße 11, 85748, Garching, Germany.
Irina NebInstitute for Translational Cardiac Surgery (INSURE), Department of Cardiovascular Surgery, German Heart Center, Technical University of Munich, 80636, Munich, Germany.
Harald LahmInstitute for Translational Cardiac Surgery (INSURE), Department of Cardiovascular Surgery, German Heart Center, Technical University of Munich, 80636, Munich, Germany.
Martina DreßenInstitute for Translational Cardiac Surgery (INSURE), Department of Cardiovascular Surgery, German Heart Center, Technical University of Munich, 80636, Munich, Germany.
Markus KraneDivision of Cardiac Surgery, Yale School of Medicine, New Haven, CT, 06510, USA.
Hendrik DietzMunich Institute of Biomedical Engineering, Technical University of Munich, Boltzmannstraße 11, 85748, Garching, Germany.
Berna ÖzkaleMicrorobotic Bioengineering Lab (MRBL), School of Computation Information and Technology, Technical University of Munich, Hans-Piloty-Straße 1, 85748, Garching, Germany.ORCID 0000-0002-3016-9363

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, the study presents a thermally activated cell-signal imaging (TACSI) microrobot, capable of photothermal actuation, sensing, and light-driven locomotion. The plasmonic soft microrobot is specifically designed for thermal stimulation of mammalian cells to investigate cell behavior under heat active conditions. Due to the integrated thermosensitive fluorescence probe, Rhodamine B, the system allows dynamic measurement of induced temperature changes. TACSI microrobots show excellent biocompatibility over 72 h in vitro, and they are capable of thermally activating single cells to cell clusters. Locomotion in a 3D workspace is achieved by relying on thermophoretic convection, and the microrobot speed is controlled within a range of 5-65 µm s

Indexed as

RoboticsAnimalsHot TemperatureHumansLasersMammalsgold-alginate nanocompositeslight-guided locomotionmobile thermometryphotothermal actuationplasmonic soft microrobotsthermal biology

Identifiers

PMID37229536
PMCPMC11468149

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.