Evidence map›Paper›PMID 37229018›Full record

ArticleAnnals of medicine and surgery (2012)2023

Nonparaneoplastic anti-NMDA receptor encephalitis in an adolescent girl: a case report.

Sharmila Ghimire, Madhur Bhattarai, Sandeep Ghimire, Kumar B Bista, Prakash Sharma, Arun Kharel, Niraj Gautam

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sharmila GhimireInstitute of Medicine.ORCID 0000-0001-7707-0670
Madhur BhattaraiInstitute of Medicine.ORCID 0000-0001-6382-1082
Sandeep GhimireInstitute of Medicine.
Kumar B BistaPokhara Academy of Health Sciences, Pokhara, Nepal.
Prakash SharmaInstitute of Medicine.
Arun KharelInstitute of Medicine.
Niraj GautamDepartment of Neurology, Institute of Medicine, Tribhuvan University, Maharajgunj.
Tribhuvan University Teaching Hospital · NPPokhara University · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti- Case presentation: A 17-year-old female presented to the hospital with an 11-day history of fever, altered behavior, abnormal body movements, and altered sensorium. Upon examination, she was found to be febrile, tachycardic, and tachypneic, with a Glasgow Coma Scale score of 8. Discussion: The diagnosis of anti-NMDA receptor encephalitis is usually confirmed by the presence of anti-NMDA receptor antibodies in the cerebrospinal fluid. The first-line treatment options include steroids, intravenous immunoglobulin, and plasmapheresis, while second-line therapies such as rituximab and cyclophosphamide may be necessary for some patients. While most patients respond well to treatment, complications can arise, and as in this case, death can occur. Conclusion: New onset symptoms like alteration in behavior, abnormal body movement, altered sensorium, and psychiatric symptoms in a young female should raise suspicion of this disease. Immunotherapy is promising; however, anticipation and management of complication are essential in reducing mortality.

Indexed as

anti-NMDA receptor encephalitisanti-NMDAR encephalitisautoimmune encephalitis

Identifiers

PMID37229018
PMCPMC10205200
OpenAlexW4364366029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.