Evidence map›Paper›PMID 37228857›Full record

ReviewFuture science OA2023

Traumatic brain injury and immunological outcomes: the double-edged killer.

Souvik Datta, Feng Lin, Lawrence D Jones, Sandeep C Pingle, Santosh Kesari, Shashaanka Ashili

Open access · goldAbstract readReview
In one paragraph

Review in Future science OA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Aquaporins: Gatekeepers of Fluid Dynamics in Traumatic Brain Injury.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Souvik DattaRhenix Lifesciences, 237 Arsha Apartments, Kalyan Nagar, Hyderabad, TG 500038, India.
Feng LinCureScience, 5820 Oberlin Drive #202, San Diego, CA 92121, USA.ORCID https://orcid.org/0000-0001-7662-423X
Lawrence D JonesCureScience, 5820 Oberlin Drive #202, San Diego, CA 92121, USA.ORCID https://orcid.org/0000-0002-8706-2014
Sandeep C PingleCureScience, 5820 Oberlin Drive #202, San Diego, CA 92121, USA.ORCID https://orcid.org/0000-0003-0124-4093
Santosh KesariSaint John's Cancer Institute, Santa Monica, CA 90404, USA.ORCID https://orcid.org/0000-0003-3772-6000
Shashaanka AshiliCureScience, 5820 Oberlin Drive #202, San Diego, CA 92121, USA.ORCID https://orcid.org/0000-0001-6335-0954
Saint John's Health Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a significant cause of mortality and morbidity worldwide resulting from falls, car accidents, sports, and blast injuries. TBI is characterized by severe, life-threatening consequences due to neuroinflammation in the brain. Contact and collision sports lead to higher disability and death rates among young adults. Unfortunately, no therapy or drug protocol currently addresses the complex pathophysiology of TBI, leading to the long-term chronic neuroinflammatory assaults. However, the immune response plays a crucial role in tissue-level injury repair. This review aims to provide a better understanding of TBI's immunobiology and management protocols from an immunopathological perspective. It further elaborates on the risk factors, disease outcomes, and preclinical studies to design precisely targeted interventions for enhancing TBI outcomes.

Indexed as

immune responseimmunopathologymanagement protocolsneuroinflammationrisk factorstraumatic brain injury (TBI)

Identifiers

PMID37228857
PMCPMC10203904
OpenAlexW4378347865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.