Evidence map›Paper›PMID 37228738›Full record

ArticleFrontiers in public health2023

Epidemiological characteristics and risk factors of multidrug-resistant tuberculosis in Luoyang, China.

Zhenzhen Wang, Yi Hou, Tengfei Guo, Tao Jiang, Liang Xu, Hongxia Hu, Zhanqin Zhao, Yun Xue

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhenzhen WangThe First Affiliated Hospital and Clinical Medical College, Henan University of Science and Technology, Luoyang, China.
Yi HouLuoyang Center for Disease Control and Prevention, Luoyang, China.
Tengfei GuoThe First Affiliated Hospital and Clinical Medical College, Henan University of Science and Technology, Luoyang, China.
Tao JiangThe First Affiliated Hospital and Clinical Medical College, Henan University of Science and Technology, Luoyang, China.
Liang XuSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, China.
Hongxia HuThe First Affiliated Hospital and Clinical Medical College, Henan University of Science and Technology, Luoyang, China.
Zhanqin ZhaoAnimal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Yun XueSchool of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang, China.
First Affiliated Hospital of Henan University of Science and Technology · CNHenan University of Science and Technology · CNLuoyang Institute of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aimed to examine the prevalence of multidrug-resistant tuberculosis (MDR-TB) in Luoyang, China, identify related risk factors, inform clinical practices, and establish standardized anti-tubercular treatment regimens. Methods: We conducted a retrospective analysis of high-resolution melting curve (HRM) data from 17,773 cases (2,748 of which were positive) between June 2019 and May 2022 to assess the prevalence of MDR-TB and to identify its associated risk factors. Results: Between June 2019 and May 2022, out of the 17,773 HRM results, 2,748 were HRM-positive, and 312 were MDR-TB cases. The detection rates for HRM-positive and MDR-TB were 17.0 and 12.1% for males, and 12.4 and 8.2% for females, respectively. The MDR-TB detection rate was higher in the urban areas (14.6%) than in the rural areas (10.6%) and more common among individuals under 51 years of age (14.1%) than those over 50 years of age (9.3%). Notably, the rate of detecting MDR-TB was 18.3% higher in new male patients than in new female patients, which was at 10.6%, and this difference was statistically significant ( Conclusion: Local TB infections are complex and diverse; therefore, more comprehensive monitoring methods are needed to curb the spread of MDR-TB.

Indexed as

Mycobacterium tuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsChinaFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedRetrospective StudiesRisk FactorsAntitubercular Agentsepidemiologyhigh-resolution melting curve (HRM)multidrug resistant tuberculosis (MDR-TB)risk factorstransmission

Identifiers

PMID37228738
PMCPMC10203519
OpenAlexW4375950612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.