Evidence map›Paper›PMID 37228626›Full record

ArticleIranian journal of biotechnology2023

Pan-cancer Analysis Reveals SRC May Link Lipid Metabolism and Macrophages.

Zhongyuan Chen, Yaqian Xiao, Pinhong Yang, Ruisong Wang

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhongyuan ChenCollege of Life and Environmental Sciences, Hunan University of Arts and Science, Changde, Hunan, China.
Yaqian XiaoFurong College, Hunan 3Furong College, Hunan University of Arts and Science, Changde, Hunan, China.
Pinhong YangCollege of Life and Environmental Sciences, Hunan University of Arts and Science, Changde, Hunan, China.
Ruisong WangCollege of Life and Environmental Sciences, Hunan University of Arts and Science, Changde, Hunan, China.
Hunan University of Arts and Science · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: SRC is a member of the membrane-associated non-receptor protein tyrosine kinase superfamily. It has been reported to mediate inflammation and cancer. However, the exact molecular mechanism involved is still not clear. Objectives: The current study was designed to explore the prognostic landscape of Materials and Methods: Kaplan-Meier Plotter was used to detect the prognostic value of Results: Our study demonstrated that SRC expression was significantly associated with overall survival and relapse-free survival in multiple cancer types. In addition, SRC expression was significantly correlated with the immune infiltration of B cells, dendritic cells, CD4 Conclusion: These results indicate that SRC can serve as a prognostic biomarker in pan-cancer and is related to macrophages infiltration and interacts with genes involved in lipid metabolism.

Indexed as

Immune cell infiltrationLipid metabolismMacrophagesPan-cancerSRC

Identifiers

PMID37228626
PMCPMC10203188
OpenAlexW4378349045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.