Evidence map›Paper›PMID 37228571›Full record

ArticleIntegrative organismal biology (Oxford, England)2023

Protein-lipid Association in Lizard Chemical Signals.

M Mangiacotti, S Baeckens, M Fumagalli, J Martín, S Scali, R Sacchi

Open access · goldAbstract read
In one paragraph

Article in Integrative organismal biology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

M MangiacottiDepartment of Earth and Environmental Sciences, University of Pavia, Via Taramelli 24, 27100 Pavia, Italy.ORCID https://orcid.org/0000-0001-7144-3851
S BaeckensFunctional Morphology Lab, Department of Biology, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID https://orcid.org/0000-0003-2189-9548
M FumagalliDepartment of Biology and Biotechnologies "L. Spallanzani", University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.
J MartínDepartamento de Ecología Evolutiva, Museo Nacional de Ciencias Naturales, CSIC, José Gutiérrez Abascal 2, E-28006 Madrid, Spain.
S ScaliSezione Erpetologia, Museo di Storia Naturale di Milano, Corso Venezia 55, IT-20121 Milano, Italy.ORCID https://orcid.org/0000-0002-4318-751X
R SacchiDepartment of Earth and Environmental Sciences, University of Pavia, Via Taramelli 24, 27100 Pavia, Italy.ORCID https://orcid.org/0000-0002-6199-0074
University of Pavia · ITMuseo Nacional de Ciencias Naturales · ESUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical communication in terrestrial vertebrates is often built on complex blends, where semiochemical and structural compounds may form an integrated functional unit. In lizards, many species have specialized epidermal glands whose secretions are waxy, homogeneous blends of lipids and proteins, both active in communication. The intimate co-occurrence of such compounds allows us to hypothesize that they should undergo a certain degree of covariation, considering both their semiochemical role and the support-to-lipid function hypothesized for the protein fraction. In order to assess the occurrence and level of protein-lipid covariation, we compared the composition and complexity of the two fractions in the femoral gland secretions of 36 lizard species, combining phylogenetically-informed analysis with tandem mass spectrometry. We found the composition and complexity of the two fractions to be strongly correlated. The composition of the protein fraction was mostly influenced by the relative proportion of cholestanol, provitamin D

Identifiers

PMID37228571
PMCPMC10205002
OpenAlexW4378348464

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.