ArticleERJ open research2023
Application of the Rome severity classification of COPD exacerbations in a real-world cohort of hospitalised patients.
Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Immune-inflammatory profiles are associated with exercise capacity and psychological status in hospitalized patients with acute exacerbation of COPD.Scientific reports · 2026Article
- Revisiting Acute Exacerbations of Chronic Obstructive Pulmonary Disease: Insights from Applying the Rome Proposal in a North American Academic Hospital.International journal of chronic obstructive pulmonary disease · 2026Article
- Impact of a follow-up visit on two-year mortality after severe exacerbation of COPD in Finland.European clinical respiratory journal · 2026Article
- Latent Class Analysis to Identify Novel Phenotypes in Exacerbations of COPD: A Retrospective, Multicenter Cohort Study.MedComm · 2025Article
- A robust chronic obstructive pulmonary disease classification model using dragonfly optimized kernel extreme learning machine.Scientific reports · 2025Article
- Phenotypes of Exacerbations in Chronic Obstructive Pulmonary Disease.Journal of clinical medicine · 2025Review
- Hospitalization Predictors in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Post Hoc Study of a Multicentric Retrospective Analysis.Journal of clinical medicine · 2025Article
- Validation Study of Rome Criteria for Assessing COPD Exacerbation Severity and Predicting Clinical Outcomes: Turkish Thoracic Society COPD Assembly.International journal of chronic obstructive pulmonary disease · 2025Article
- Validation of the Rome Severity Classification of Chronic Obstructive Pulmonary Disease Exacerbation: A Multicenter Cohort Study.International journal of chronic obstructive pulmonary disease · 2024Article
- GOLD 2024: a brief overview of key changes.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023Article
- The Exacerbation of Chronic Obstructive Pulmonary Disease: Which Symptom is Most Important to Monitor?International journal of chronic obstructive pulmonary disease · 2023Article
- Applying the Rome Proposal on Exacerbations of Chronic Obstructive Pulmonary Disease: Does Comorbid Chronic Heart Failure Matter?International journal of chronic obstructive pulmonary disease · 2023Article
- The EXACERBANTES Study (Open respiratory archivesArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Recently, the Rome classification was proposed in which objective and readily measurable variables were integrated to mark exacerbations of COPD (ECOPD) severity. The aim of this study is to investigate the distribution of a real-world patient population with hospitalised ECOPD according to the current classification across the newly proposed severity classification. We assume that a significant proportion of hospitalised patients will have a mild or moderate event. Methods: The Rome classification was applied to a cohort of 364 COPD patients hospitalised at the Department of Respiratory Medicine of Maastricht University Medical Center (MUMC) with a severe ECOPD. Differences in in-hospital, 30- and 90-day mortality were compared between mild, moderate and severe ECOPD according to the new classification. Moreover, data were stratified by the different severity classes and compared regarding general disease characteristics and clinical parameters. Results: According to the Rome proposal, 52 (14.3%) patients had a mild ECOPD, 204 (56.0%) a moderate and 108 (29.7%) a severe ECOPD. In-hospital mortality in mild, moderate and severe events was 3.8%, 6.9% and 13.9%, respectively. Most clinical parameters indicated a significantly worse condition in patients classified in the severe group, compared to those in mild or moderate groups. Conclusion: Most of the events, traditionally all classified as severe because of the hospitalisation, were classified as moderate, while almost 15% were mild. The results of this study provide insight into the heterogeneity of hospitalised ECOPD and show that the newly proposed Rome criteria can differentiate between events with different short-term mortality rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.