Evidence map›Paper›PMID 37228239›Full record

ArticleCirculation research2023

UnWNTing the Heart: Targeting WNT Signaling in Pulmonary Arterial Hypertension.

Elena A Goncharova, Tatiana V Kudryashova, Vinicio A de Jesus Perez, Olga Rafikova

Open access · greenAbstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Piezo1 induces Wnt7bTheranostics · 2026
    Article
  3. Article
  4. Review
  5. Dissecting the lung transcriptome of pulmonary fibrosis-associated pulmonary hypertension.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Elena A GoncharovaLung Center, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, Davis School of Medicine, Davis, CA (E.A.G., T.V.K.).ORCID 0000-0001-7118-6752
Tatiana V KudryashovaLung Center, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, Davis School of Medicine, Davis, CA (E.A.G., T.V.K.).ORCID 0000-0002-2843-5554
Vinicio A de Jesus PerezDivision of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA (V.A.d.J.P.).ORCID 0000-0001-5532-8247
Olga RafikovaDepartment of Medicine, Division of Endocrinology, University of Arizona College of Medicine, Tucson, AZ (O.R.).
University of California, Davis · USStanford University · USUniversity of Arizona · US

Funding

The Wnt7a/ROR2 axis in the pathogenesis of pulmonary arterial hypertensionR01HL134776 · NHLBI · STANFORD UNIVERSITY · PI DE JESUS PEREZ, VINICIO A · 2017 to 2025
$5.0M
Endothelial-pericyte interactions in the pathogenesis of pulmonary arterial hypertensionR01HL139664 · NHLBI · STANFORD UNIVERSITY · PI DE JESUS PEREZ, VINICIO A · 2018 to 2025
$4.7M
HIPPO Signaling in Pulmonary Arterial HypertensionR01HL130261 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GONCHAROVA, ELENA · 2016 to 2023
$3.5M
Mitochondrial Dysfunction in Pulmonary HypertensionR01HL160666 · NHLBI · UNIVERSITY OF ARIZONA · PI Olga Rafikova · 2022 to 2026
$3.3M
GATA-6 in pulmonary arterial hypertensionR01HL150638 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GONCHAROVA, ELENA, TROJANOWSKA, MARIA · 2020 to 2023
$2.6M
HMGBG1 and Gender Difference in Pulmonary Arterial HypertensionR01HL133085 · NHLBI · UNIVERSITY OF ARIZONA · PI RAFIKOVA, OLGA · 2016 to 2020
$1.9M
HIPK2 signaling in Pulmonary Arterial HypertensionR01HL166932 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Tatiana V Kudryashova · 2023 to 2026
$1.6M
NHLBI NIH HHS R01 HL130261NHLBI NIH HHS R01 HL133085NHLBI NIH HHS R01 HL134776NHLBI NIH HHS R01 HL139664NHLBI NIH HHS R01 HL150638NHLBI NIH HHS R01 HL160666NHLBI NIH HHS R01 HL166932
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hypertension, PulmonaryPulmonary Arterial HypertensionHeartHumansPrognosisPulmonary ArteryThoraxWnt Signaling Pathwaychronic diseaseconstrictionEditorialprognosispulmonary arterial hypertension

Identifiers

PMID37228239
PMCPMC10213998
OpenAlexW4378194672

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.