SynthesisPloS one2023
Prevalence of osteoporosis in spinal surgery patients older than 50 years: A systematic review and meta-analysis.
Synthesis in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed, 39 citations in OpenAlex.
- Development and evaluation of a simple CT-based DXA triage score for osteoporosis in candidates for lumbar spine surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Risk Factors for Proximal Junctional Kyphosis in Osteoporotic Versus Non-Osteoporotic Patients After Adult Spinal Deformity Surgery.Journal of clinical medicine · 2026Article
- Impact of Preoperative Teriparatide Use on Proximal Junctional Kyphosis Prevention in Osteopenic/Osteoporotic Patients Undergoing Adult Spinal Deformity Surgery: A Propensity Score-Matched Study.Journal of clinical medicine · 2026Article
- Streamlining the MRI-Derived Vertebral Bone Quality Score for Preoperative Osteoporosis and Osteopenia Screening.Global spine journal · 2026Article
- The impact of osteoporosis on preoperative presentation in adult spinal deformity patients undergoing surgical correction: a retrospective study.Spine deformity · 2026Article
- A bone optimization rheumatology clinic increases anabolic bone agent use and reduces mechanical complications in adult spinal deformity surgery.Spine deformity · 2026Article
- Shaping the future of spinal implants: advancing bioactive composites with 3D printing for next-generation surgical care.Journal of orthopaedic surgery and research · 2026Review
- Lumbar MRI-Based Deep Learning for Osteoporosis Prediction.Diagnostics (Basel, Switzerland) · 2026Article
- Biomechanical Analysis Comparison of Different Cervical Posterior Screw Fixation Techniques: A Finite Element Study.Neurospine · 2026Article
- Biomechanical optimization of pedicle screw trajectories in osteoporotic lumbar fusion: finite element analysis and validation of robotic-assisted implementation.Journal of robotic surgery · 2025Article
- Bone Optimization for Perioperative Spine Patients: A Multidisciplinary Approach at a Single Academic Center.Journal of clinical medicine · 2025Article
- Microenvironment-responsive hydrogels for spatiotemporal delivery of epigallocatechin gallate and BMP-2 to promote osteoporotic bone defect repair.Materials today. Bio · 2025Article
- Predicting osteoporosis-related complications in lumbar spine surgery using Hounsfield unit and vertebral bone quality scores: A 5-Year follow-up study with principal component analysis insights.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Impact of osteoporosis on perioperative complications in patients undergoing surgical treatment for lumbar spinal stenosis: a nationwide retrospective study.Asian spine journal · 2025Article
- Osteoporosis in Adult Patients Undergoing Spinal Reconstructive Surgery: Associated Complications and Management.Global spine journal · 2025Article
- Determining the bone mineral density in patients with degenerative lumbar scoliosis: CT hounsfield unit values versus MRI vertebral bone quality scores.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Fracture of Fused Vertebrae More Than 20 Years After Anterior Cervical Fusion: A Case Report.Cureus · 2025Article
- Fatty infiltration in the multifidus predicts screw-loosening following short-segment decompression and fusion: proof of why we should protect and rehabilitate the paraspinal muscles.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Impact of Frailty and Other Factors as Estimated by HU to Predict Response to Anabolic Bone Medications.Journal of clinical medicine · 2025Article
- Undetected low bone mineral density in patients undergoing lumbar fusion surgery-prevalence and risk factors.North American Spine Society journal · 2025Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIn spine surgery, poor bone condition is associated with several complications like adjacent segment fractures, proximal junctional kyphosis, and screw loosening. Our study explored the prevalence of osteoporosis in spinal surgery patients older than 50 years through a systematic review and meta-analysis.
methodsThis systematic review and meta-analysis were conducted according to the PRISMA criteria. Three electronic databases, including PubMed, EMBASE, and Web of Science, were searched from inception to August 2022. We used the random-effects model to calculate the overall estimates, and the heterogeneity was measured using Cochran's Q and I2 tests. Meta-regression and subgroup analyses were used to determine the source of the heterogeneity.
resultsBased on the inclusion and criteria, we chose ten studies with 2958 individuals for our analysis. The prevalence of osteoporosis, osteopenia, and osteoporosis/osteopenia in the spinal surgery patients was 34.2% (95%CI: 24.5%-44.6%), 43.5% (95%CI: 39.8%-47.2%), and 78.7% (95%CI: 69.0%-87.0%), respectively. Regarding different diagnoses, the prevalence was highest in patients with lumbar scoliosis (55.8%; 95%CI: 46.8%-64.7%) and the lowest in patients with cervical disc herniation (12.9%; 95%CI: 8.1%-18.7%). In age groups 50-59, 50-69,70-79, the prevalence was 27.8%, 60.4%, 75.4% in females, and 18.9%, 17.4%, 26.1% in males.
conclusionsThis study showed a high prevalence of osteoporosis in patients undergoing spine surgery, especially in females, people of older age, and patients who received degenerative scoliosis and compression fractures. Current osteoporosis screening standards for patients undergoing spine surgery may not be adequate. Orthopedic specialists should make more efforts regarding preoperative osteoporosis screening and treatment.
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