Evidence map›Paper›PMID 37227671›Full record

ArticleJournal of neurovirology2023

Case report of Usutu virus infection in an immunocompromised patient in Italy, 2022.

Paolo Gaibani, Nicole Barp, Marco Massari, Emanuele Alberto Negri, Giada Rossini, Caterina Vocale, Chiara Trenti, Altea Gallerani, Samuele Cantergiani, Federico Romani and 3 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of neurovirology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

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  10. MITD1 is a brain-specific interferon-inducible factor that inhibits flavivirus replication.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Paolo GaibaniOperative Unit of Clinical Microbiology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy. paolo.gaibani@unibo.it.ORCID 0000-0003-3791-8635
Nicole BarpOperative Unit of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Marco MassariOperative Unit of Infectious Diseases, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.
Emanuele Alberto NegriOperative Unit of High Intensity Care, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.
Giada RossiniOperative Unit of Clinical Microbiology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Caterina VocaleOperative Unit of Clinical Microbiology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Chiara TrentiOperative Unit of High Intensity Care, Azienda USL-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.
Altea GalleraniOperative Unit of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Samuele CantergianiOperative Unit of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Federico RomaniOperative Unit of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Mattia SimionOperative Unit of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Cristina MussiniOperative Unit of Infectious Diseases, University of Modena and Reggio Emilia, Modena, Italy.
Tiziana LazzarottoOperative Unit of Clinical Microbiology, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
University of Modena and Reggio Emilia · ITAzienda USL di Bologna · ITAzienda Sanitaria Unità Locale di Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Usutu virus (USUV) is an arthropod-borne flavivirus emerged in Africa in 1950s and in Eruope in 1990s causing a massive number of birds' deaths. The role of USUV as human pathogen has been only recently hypothesized and cases of USUV infection in humans remain limited and often related to immunocompromised subjects. Herein, we report a case of USUV meningoencephalitis infection in an immunocompromised patient with no history of previous flavivirus infection. The infection due to USUV evolved rapidly since hospital admission thus resulting fatal in few days after symptoms onset and, although not proven, a suspected bacteria co-infection has been hypothesized. Based on these findings, we suggested that when USUV meningoencephalitis is suspected in countries endemic, careful attention should be applied to neurological syndromes during summer months especially among immunocompromised patients.

Indexed as

FlavivirusFlavivirus InfectionsHumansImmunocompromised HostItalyArbovirusEndemicFlavivirusHuman caseItaly

Identifiers

PMID37227671
PMCPMC10211289
OpenAlexW4378172284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.