Evidence map›Paper›PMID 37227569›Full record

SynthesisJournal of assisted reproduction and genetics2023

Platelet distribution width and the risk of unexplained recurrent pregnancy loss: a meta-analysis.

Yan Shi, Dongmei Xu

Abstract readMeta-Analysis
In one paragraph

Synthesis in Journal of assisted reproduction and genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yan ShiDepartment of Obstetrics and Gynecology, Chongqing Health Center for Women and Children, No. 120 Longshan Road, Yubei District, Chongqing, 400010, China.
Dongmei XuDepartment of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, No. 120 Longshan Road, Yubei District, Chongqing, 400010, China. dongmeixu2392@163.com.ORCID http://orcid.org/0000-0003-3196-9220

Funding

Application of aspirin or low molecular weight heparin in the treatment of unexplained recurrent early pregnancy failure 2021MSXM173
6 · The paper itself

Abstract

objectiveChanges of platelet distribution width (PDW) have been observed in women with unexplained recurrent pregnancy loss (URPL). However, relevant previous studies showed inconsistent results. We performed a meta-analysis to comprehensively evaluate the association between PDW and URPL.

methodsObservational studies reporting the difference of PDW between women with and without URPL were retrieved by searching PubMed, Embase, Web of Science, Wanfang, and CNKI. A random-effect model was used to pool the results by incorporating potential heterogeneity.

resultsEleven case-control studies with 1847 women with URPL and 2475 healthy women were included. Age was matched for all studies between cases and controls. Pooled results showed women with URPL had significantly increased level of PDW (mean difference [MD]: 1.54%, 95% CI: 1.04 to 2.03, p < 0.05; I

conclusionsWomen with URPL had significantly increased levels of PDW compared to healthy women without URPL, which suggest that higher PDW may predict the risk of URPL.

Indexed as

Abortion, HabitualCase-Control StudiesFemaleHumansObservational Studies as TopicPregnancyPubMedMeta-analysisPlatelet distribution widthPlatelet functionRisk factorUnexplained recurrent pregnancy loss

Identifiers

PMID37227569
PMCPMC10352223

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.