Evidence map›Paper›PMID 37227557›Full record

ArticleJournal of molecular histology2023

EGF-receptor phosphorylation and downstream signaling are activated by genistein during subacute liver damage.

Erick Ayala-Calvillo, Lourdes Rodríguez-Fragoso, Elizabeth Álvarez-Ayala, Alfonso Leija-Salas

Open access · hybridAbstract read
In one paragraph

Article in Journal of molecular histology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Erick Ayala-CalvilloFacultad de Farmacia, Universidad Autónoma del Estado de Morelos. Av Universidad, 1001 Col. Chamilpa CP 62210, Cuernavaca, Morelos, México.
Lourdes Rodríguez-FragosoFacultad de Farmacia, Universidad Autónoma del Estado de Morelos. Av Universidad, 1001 Col. Chamilpa CP 62210, Cuernavaca, Morelos, México.
Elizabeth Álvarez-AyalaFacultad de Farmacia, Universidad Autónoma del Estado de Morelos. Av Universidad, 1001 Col. Chamilpa CP 62210, Cuernavaca, Morelos, México.
Alfonso Leija-SalasCentro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Av. Universidad 2001, CP62210 Col. Chamilpa, Morelos, Cuernavaca, Mexico. leija@ccg.unam.mx.
Universidad Autónoma del Estado de Morelos · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidermal growth factor receptor (EGFR) plays an important role on hepatic protection in acute and chronic liver injury. The aim of this study was to investigate the role of genistein on EGFR expression, phosphorylation and signaling pathways in experimental subacute liver damage induced by carbon tetrachloride (CCl

Indexed as

GenisteinLiver DiseasesAnimalsCytokinesEpidermal Growth FactorErbB ReceptorsLiverMalePhosphorylationProliferating Cell Nuclear AntigenRatsRats, WistarSignal TransductionCytokinesEpidermal Growth FactorErbB ReceptorsGenisteinProliferating Cell Nuclear AntigenEGFR signaling pathwaysGenisteinLiver damage.

Identifiers

PMID37227557
PMCPMC10232619
OpenAlexW4378173368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.