Evidence map›Paper›PMID 37227494›Full record

ArticlePlant cell reports2023

Genome-wide association study reveals the genetic variation and candidate gene for grain calcium content in bread wheat.

Jianhui Ma, Jingjie Ren, Xuqing Yuan, Meng Yuan, Daijing Zhang, Chunxi Li, Qingdong Zeng, Jianhui Wu, Dejun Han, Lina Jiang

Abstract read
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In one paragraph

Article in Plant cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Content characteristics and genetic architecture of macronutrient signatures in cottonseed.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jianhui MaCollege of Life Science, Henan Normal University, Xinxiang, 453007, Henan, China. cricaas@163.com.
Jingjie RenCollege of Life Science, Henan Normal University, Xinxiang, 453007, Henan, China.
Xuqing YuanCollege of Life Science, Henan Normal University, Xinxiang, 453007, Henan, China.
Meng YuanCollege of Life Science, Henan Normal University, Xinxiang, 453007, Henan, China.
Daijing ZhangCollege of Life Science, Henan Normal University, Xinxiang, 453007, Henan, China.
Chunxi LiCollege of Life Science, Henan Normal University, Xinxiang, 453007, Henan, China.
Qingdong ZengState Key Laboratory of Crop Stress Biology in Arid Areas, Northwest A&F University, Yangling, Xianyang, 712100, Shanxi, China.
Jianhui WuState Key Laboratory of Crop Stress Biology in Arid Areas, Northwest A&F University, Yangling, Xianyang, 712100, Shanxi, China.
Dejun HanState Key Laboratory of Crop Stress Biology in Arid Areas, Northwest A&F University, Yangling, Xianyang, 712100, Shanxi, China. handj@nwsuaf.edu.cn.
Lina JiangCollege of Life Science, Henan Normal University, Xinxiang, 453007, Henan, China. jiangln@htu.edu.cn.ORCID http://orcid.org/0000-0001-9432-7044
Henan Normal University · CNNorthwest A&F University · CNNorth West Agriculture and Forestry University · CN

Funding

State Key Laboratory of Wheat and Maize Crop Science CSBAA2020001the National Key Research and Development Program of China 2017YFD0301101the National Key Research and Development Program of China 2018YFD0300703-2
6 · The paper itself

Abstract

key messageThis study provides important information on the genetic basis of GCaC in wheat, thus contributing to breeding efforts to improve the nutrient quality of wheat. Calcium (Ca) plays important roles in the human body. Wheat grain provides the main diet for billions of people worldwide but is low in Ca content. Here, grain Ca content (GCaC) of 471 wheat accessions was determined in four field environments. A genome-wide association study (GWAS) was performed to reveal the genetic basis of GCaC using the phenotypic data form four environments and a wheat 660 K single nucleotide polymorphism (SNP) array. Twelve quantitative trait locus (QTLs) for GCaC were identified on chromosomes 1A, 1D, 2A, 3B, 6A, 6D, 7A, and 7D, which was significant in at least two environments. Haplotype analysis revealed that the phenotypic difference between the haplotypes of TraesCS6D01G399100 was significant (P ≤ 0.05) across four environments, suggesting it as an important candidate gene for GCaC. This research enhances our understanding of the genetic architecture of GCaC for further improving the nutrient quality of wheat.

Indexed as

CalciumGenome-Wide Association StudyBreadChromosome MappingEdible GrainGenetic VariationHumansPhenotypePlant BreedingPolymorphism, Single NucleotideTriticumCalciumGenome-wide association studyGrain Ca ContentTriticum aestivum L.

Identifiers

PMID37227494
OpenAlexW4378173085

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.