Evidence map›Paper›PMID 37227147›Full record

ArticleMicrobiology spectrum2023

Assessment of Enterovirus Antibodies during Early Childhood Using a Multiplex Immunoassay.

N V V Jouppila, J Lehtonen, E Seppälä, L Puustinen, S Oikarinen, O H Laitinen, M Knip, H Hyöty, V P Hytönen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

N V V JouppilaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
J LehtonenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
E SeppäläFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
L PuustinenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
S OikarinenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
O H LaitinenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
M KnipResearch Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
H HyötyFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
V P HytönenFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID 0000-0002-9357-1480
Tampere University · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enteroviruses are a group of positive single-stranded viruses that belong to the Picornaviridae family. They regularly infect humans and cause symptoms ranging from the common cold and hand-foot-and-mouth disease to life-threatening conditions, such as dilated cardiomyopathy and poliomyelitis. Enteroviruses have also been associated with chronic immune-mediated diseases, such as type 1 diabetes, celiac disease, and asthma. Studying these disease-pathogen connections is challenging due to the high prevalence of enterovirus infections in the population and the transient appearance of the virus during the acute infection phase, which limit the identification of the causative agent via methods based on the virus genome. Serological assays can detect the antibodies induced by acute and past infections, which is useful when direct virus detection is not possible. We describe in this immuno-epidemiological study how the antibody levels against VP1 proteins from eight different enterovirus types, representing all seven of the human infecting enterovirus species, vary over time. VP1 responses first significantly (

Indexed as

Common ColdEnterovirusEnterovirus InfectionsPoliomyelitisAnimalsAntibodies, ViralAntigens, ViralChildChild, PreschoolHumansImmunoassayInfantAntibodies, ViralAntigens, Viralantigenchildrendiagnosticsenterovirushumoral responsemultiplex assayserology

Identifiers

PMID37227147
PMCPMC10269870
OpenAlexW4378173033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.