Evidence map›Paper›PMID 37227051›Full record

ArticleeLife2023

Homeostatic control of an iron repressor in a GI tract resident.

Yuanyuan Wang, Yinhe Mao, Xiaoqing Chen, Xinhuang Huang, Zhongyi Jiang, Kaiyan Yang, Lixing Tian, Tong Jiang, Yun Zou, Xiaoyuan Ma and 7 more

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yuanyuan Wang *The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0001-7464-7446
Yinhe Mao *The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Xiaoqing ChenThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Xinhuang HuangThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Zhongyi JiangDepartment of General Surgery, Shanghai General Hospital, Shanghai, China.
Kaiyan YangThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Lixing TianState Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Army Medical Center (Daping Hospital), Chongqing, China.
Tong JiangThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Yun ZouThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Xiaoyuan MaState Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Army Medical Center (Daping Hospital), Chongqing, China.
Chaoyue XuThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Zili ZhouThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Xianwei WuThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Lei PanThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Huaping LiangState Key Laboratory of Trauma, Burns and Combined Injury, Department of Wound Infection and Drug, Army Medical Center (Daping Hospital), Chongqing, China.
Lin ZhongDepartment of General Surgery, Shanghai General Hospital, Shanghai, China.
Changbin ChenThe Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Unit of Pathogenic Fungal Infection & Host Immunity, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.ORCID 0000-0002-7961-3488

Funding

Ministry of Science and Technology (China) Key R&D Program 2022YFC2303200Ministry of Science and Technology (China) Key R&D Program 2022YFC2304700National Natural Science Foundation of China 31600119National Natural Science Foundation of China 32070146National Natural Science Foundation of China 32170195National Postdoctoral Fellowship No.312780Natural Science Foundation of Shanghai 15ZR1444400Natural Science Foundation of Shanghai 20ZR1463800Shanghai Post-doctoral Excellence Program No.2022647The MOST Key R&D Program of China 2022YFC2303200The MOST Key R&D Program of China 2022YFC2304700The National Natural Science Foundation 31600119The National Natural Science Foundation 32070146The National Natural Science Foundation 32170195The Natural Science Foundation of Shanghai 15ZR1444400The Natural Science Foundation of Shanghai 20ZR1463800The Open Project of the State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University SKLKF201803The Shanghai Municipal Science and Technology Major Project 2019SHZDZX02The Special Program of PLA 19SWAQ18
6 · The paper itself

Abstract

The transition metal iron plays a crucial role in living cells. However, high levels of iron are potentially toxic through the production of reactive oxygen species (ROS), serving as a deterrent to the commensal fungus

Indexed as

Fungal ProteinsIronAnimalsCandida albicansGastrointestinal TractGene Expression Regulation, FungalHomeostasisMiceReactive Oxygen SpeciesFungal ProteinsIronReactive Oxygen SpeciesCandida albicanscellular detoxificationHap43infectious diseaseironmicrobiologyoxidative damage

Identifiers

PMID37227051
PMCPMC10259491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.