Evidence map›Paper›PMID 37226909›Full record

ArticleSubstance abuse

A National Study of Homelessness, Social Determinants of Health, and Treatment Engagement Among Outpatient Medication for Opioid Use Disorder-Seeking Individuals in the United States.

Marina Gaeta Gazzola, Iain D Carmichael, Nicholaus J Christian, Xiaoying Zheng, Lynn M Madden, Declan T Barry

Erratum issuedOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Treating cancer-related symptoms in patients exhibiting nonmedical opioid use behaviours: a retrospective chart review study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  11. Socioeconomic Deprivation and Opioid Consumption: An Analysis Across England.International journal of environmental research and public health · 2025
    Review
  12. Review
  13. Observational
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Marina Gaeta GazzolaAPT Foundation, Inc., New Haven, CT, USA.
Iain D CarmichaelDepartment of Statistics, University of California at Berkeley, Berkeley, CA, USA.
Nicholaus J ChristianDepartment of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Xiaoying ZhengAPT Foundation, Inc., New Haven, CT, USA.
Lynn M MaddenAPT Foundation, Inc., New Haven, CT, USA.
Declan T BarryAPT Foundation, Inc., New Haven, CT, USA.
Yale University · USAPT Foundation · USNew York University · USUniversity of California, San Francisco · US

Funding

HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research CentersRM1DA055310 · NIDA · YALE UNIVERSITY · PI BARRY, DECLAN T., BECKER, WILLIAM C · 2021 to 2025
$12.9M
The Collaboration Linking Opioid Use Disorder and Sleep ("CLOUDS") StudyU01HL150596 · NHLBI · YALE UNIVERSITY · PI BARRY, DECLAN T., REDEKER, NANCY S · 2019 to 2024
$5.1M
6 · The paper itself

Abstract

backgroundHomelessness is an important social determinant of health (SDOH), impacting health outcomes for many medical conditions. Although homelessness is common among people with opioid use disorder (OUD), few studies systematically evaluate homelessness and other SDOH among people enrolled in standard of care treatment for OUD, medication for opioid use disorder (MOUD), or examine whether homelessness affects treatment engagement.

methodsUsing data from the 2016 to 2018 U.S. Treatment Episode Dataset Discharges (TEDS-D), patient demographic, social, and clinical characteristics were compared between episodes of outpatient MOUD where homelessness was reported at treatment enrollment versus independent housing using pairwise tests adjusted for multiple testing. A logistic regression model examined the relationship between homelessness and treatment length and treatment completion while accounting for covariates.

resultsThere were 188 238 eligible treatment episodes. Homelessness was reported in 17 158 episodes (8.7%). In pairwise analysis, episodes involving homelessness were significantly different from those involving independent living on most demographic, social, and clinical characteristics, with significantly greater social vulnerability in most SDOH variables (

conclusionsPatients reporting homelessness at treatment entry in outpatient MOUD in the U.S. represent a clinically distinct and socially vulnerable population from those not reporting homelessness. Homelessness independently predicts poorer engagement in MOUD confirming that homelessness may be an independent predictor for MOUD treatment discontinuation nationally.

Indexed as

Ill-Housed PersonsOpioid-Related DisordersHumansLogistic ModelsOutpatientsSocial Determinants of Healthbuprenorphinehomelessnesshousingmedications for opioid use disordermethadoneopioid use disorder

Identifiers

PMID37226909
OpenAlexW4367844662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.