Evidence map›Paper›PMID 37226581›Full record

ArticleOphthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)2023

Utilising a visual image quality metric to optimise spectacle prescriptions for eyes with keratoconus.

Elizabeth L S Bell, Gareth D Hastings, Lan Chi Nguyen, Raymond A Applegate, Jason D Marsack

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Impact of contact lens correction on wavefront aberrations and vision quality in keratoconus.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Review
  3. Non-orthogonal spectacle correction for irregular astigmatism.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  4. Dioptric differences between clinically determined and metric-optimised refractions for adults with Down syndrome.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elizabeth L S BellUniversity of Houston College of Optometry, Houston, Texas, USA.
Gareth D HastingsUniversity of Houston College of Optometry, Houston, Texas, USA.ORCID 0000-0001-8959-5984
Lan Chi NguyenUniversity of Houston College of Optometry, Houston, Texas, USA.
Raymond A ApplegateUniversity of Houston College of Optometry, Houston, Texas, USA.
Jason D MarsackUniversity of Houston College of Optometry, Houston, Texas, USA.ORCID 0000-0002-2774-7724
University of Houston · US

Funding

Research Programming ModuleP30EY007551 · NEI · UNIVERSITY OF HOUSTON · PI LAURA J. FRISHMAN · 1988 to 2026
$16.4M
The Role of Galectins in Corneal Hem- and LymphangiogenesisR01EY007088 · NEI · TUFTS UNIVERSITY BOSTON · PI PANJWANI, NOORJAHAN · 1987 to 2015
$3.6M
Optical aberration and visual performance in highly aberrated eyesR01EY019105 · NEI · UNIVERSITY OF HOUSTON · PI APPLEGATE, RAYMOND A, MARSACK, JASON D · 2009 to 2018
$2.9M
SHORT TERM TRAINING--STUDENTS IN HEALTH PROFESSIONST35EY007088 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI FRISHMAN, LAURA J. · 1985 to 2025
$2.3M
FMRI STUDIES;VISUAL EXPERIENCE AND NEURONAL CHANGESF32EY007088 · NEI · MAX PLANCK INST/BIOLOGICAL CYBERNETICS · PI TOLIAS, ANDREAS SAVAS · 2000 to 2003
$116k
NEI NIH HHS EY019105NEI NIH HHS EY07088NEI NIH HHS EY07551NEI NIH HHS F32 EY007088NEI NIH HHS P30 EY007551NEI NIH HHS R01 EY007088NEI NIH HHS R01 EY019105NEI NIH HHS T35 EY007088
6 · The paper itself

Abstract

purposeTo compare optical performance, visual performance, and patient-perceived quality of vision with: (1) spectacles determined using subjective refraction and (2) spectacles determined using an objective optimisation method based on wavefront aberration data for eyes with keratoconus.

methodsThirty-seven eyes (20 subjects) with keratoconus underwent both subjective refraction and uncorrected wavefront aberration measurement. Wavefront aberration data were used to objectively identify a sphero-cylindrical refraction that optimised the visual image quality metric visual Strehl ratio (VSX). The two refractions were assembled in trial frames and worn by the subject in a random order. High-contrast visual acuity (VA), letter contrast sensitivity (CS), and the patient's short-term subjective preference were recorded for each prescription.

resultsMedian magnitude of the dioptric difference (a measure of similarity between the subjective and objective refractions) was 2.77 D (range = 0.21-20.44 D, first quartile = 1.02 D, third quartile = 4.36 D). Sixty-eight per cent of eyes had better VA with the objective refraction and 32% of eyes gained more than one line of VA. Monocularly, objective refraction was preferred 68% of the time when looking at a distant acuity chart and 76% of the time when viewing a real-world dynamic scene.

conclusionsObjective refraction based on visual image quality derived from wavefront aberration data can be valuable in the determination of monocular spectacle refractions for individuals with keratoconus.

Indexed as

KeratoconusEyeglassesHumansPrescriptionsRefraction, OcularVisual Acuitykeratoconusobjective refractionsubjective refractionvisual image quality

Identifiers

PMID37226581
PMCPMC10563113
OpenAlexW4378173264

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.