Evidence map›Paper›PMID 37226566›Full record

ArticleYonsei medical journal2023

Short-Term Outcomes and Cost-Effectiveness between Long-Course Chemoradiation and Short-Course Radiotherapy for Locally Advanced Rectal Cancer.

Min Soo Cho, Hyeon Woo Bae, Jee Suk Chang, Seung Yoon Yang, Tae Hyun Kim, Woong Sub Koom, Sang Joon Shin, Gyu-Seog Choi, Nam Kyu Kim

Open access · goldAbstract readComparative Study
In one paragraph

Article in Yonsei medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Min Soo ChoThe Division of Colon and Rectal Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7310-4893
Hyeon Woo BaeThe Division of Colon and Rectal Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8140-8176
Jee Suk ChangDepartment of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7685-3382
Seung Yoon YangThe Division of Colon and Rectal Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8129-7712
Tae Hyun KimGraduate School of Public Health, Yonsei University, Seoul, Korea.ORCID https://orcid.org/0000-0003-1053-8958
Woong Sub KoomDepartment of Radiation Oncology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9435-7750
Sang Joon ShinThe Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5350-7241
Gyu-Seog ChoiThe Division of Colon and Rectal Surgery, Department of Surgery, Kyungpook National University Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0001-5476-4610
Nam Kyu KimThe Division of Colon and Rectal Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea. namkyuk@yuhs.ac.ORCID https://orcid.org/0000-0003-0639-5632
Yonsei University · KRKyungpook National University Medical Center · KR

Funding

Boryung Co., Ltd.
6 · The paper itself

Abstract

purposeLong-course chemoradiotherapy (LCRT) has been widely recommended in a majority of rectal cancer patients. Recently, encouraging data on short-course radiotherapy (SCRT) for rectal cancer has emerged. In this study, we aimed to compare these two methods in terms of short-term outcomes and cost analysis under the Korean medical insurance system. MATERIALS AND

methodsSixty-two patients with high-risk rectal cancer, who underwent either SCRT or LCRT followed by total mesorectal excision (TME), were classified into two groups. Twenty-seven patients received 5 Gy×5 with two cycles of XELOX (capecitabine 1000 mg/m² and oxaliplatin 130 mg/m² every 3 weeks) followed by TME (SCRT group). Thirty-five patients received capecitabine-based LCRT followed by TME (LCRT group). Short-term outcomes and cost estimation were assessed between the two groups.

resultsPathological complete response was achieved in 18.5% and 5.7% of patients in the SCRT and LCRT groups, respectively (

conclusionSCRT was well-tolerated and achieved favorable short-term outcomes. In addition, SCRT showed significant reduction in the total cost of care and distinguished cost-effectiveness compared to LCRT.

Indexed as

ChemoradiotherapyRadiotherapyRectal NeoplasmsAsian PeopleCapecitabineCost-Benefit AnalysisHumansNeoplasms, Second PrimaryProctectomyCapecitabinecost effectivenesslong-course chemoradiationRectal cancershort course radiotherapy

Identifiers

PMID37226566
PMCPMC10232996
OpenAlexW4378085908

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.