Evidence map›Paper›PMID 37226461›Full record

Trial reportThe Journal of international medical research2023

Effect of different modes of administration of dexmedetomidine on the quality of recovery in ambulatory thyroidectomy: a randomized, controlled trial.

Pei Gao, Wen Chen, Jin Rao, Chen Chen, Yao Lu, Yuan-Hai Li

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of international medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Pei GaoDepartment of Anaesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China.ORCID 0000-0002-5117-8373
Wen ChenDepartment of Anaesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China.
Jin RaoDepartment of Anaesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China.
Chen ChenDepartment of Anaesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China.
Yao LuDepartment of Anaesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China.
Yuan-Hai LiDepartment of Anaesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the effects of two different administration methods of dexmedetomidine (DEX) used as an adjuvant to ropivacaine in ultrasound-guided bilateral intermediate cervical plexus block (CPB) in terms of efficacy and the duration of postoperative analgesia in patients undergoing ambulatory thyroidectomy.

methodsThis double-blind, randomized study enrolled patients who underwent thyroidectomy with ultrasound-guided bilateral intermediate CPB. Patients were randomized to receive either perineural administration of dexmedetomidine (group DP) or intravenous pumping of dexmedetomidine (group DI). The 40-item Quality of Recovery (QoR-40) questionnaire was used to assess the primary endpoint, which was the global QoR-40 score 24 h after the operation.

resultsSixty patients were randomized equally into the two groups. The total QoR-40 score 24 h postoperatively was significantly higher in group DP than group DI (160.6 ± 9.1 versus 152.8 ± 7.9, respectively). Dimensions of physical comfort and pain scores were significantly higher in group DP than group DI. The visual analogue scale pain score scores were significantly lower in group DP than group DI at 12 and 24 h postoperatively.

conclusionsDEX as an adjuvant to ropivacaine in ultrasound-guided intermediate CPB can improve the QoR-40 score and prolong postoperative analgesia.Trial registration number: ChiCTR2000031264 at www.chictr.org.cn on 26 March 2020.

Indexed as

DexmedetomidineThyroidectomyAdjuvants, ImmunologicHumansPainRopivacaineAdjuvants, ImmunologicDexmedetomidineRopivacaineambulatoryDexmedetomidinenauseaQoR-40thyroidectomyvomiting

Identifiers

PMID37226461
PMCPMC10226315
OpenAlexW4378172304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.