Evidence map›Paper›PMID 37226208›Full record

ArticleBMC pediatrics2023

Dose frequency randomized controlled trial for Dynamic Temporal and Tactile Cueing (DTTC) treatment for childhood apraxia of speech: protocol paper.

Jenya Iuzzini-Seigel, Julie Case, Maria I Grigos, Shelley L Velleman, Donna Thomas, Elizabeth Murray

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05675306 (Dose Frequency Randomized Control Trial for Dynamic Temporal and Tactile Cueing), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05675306 naactive not recruitingnot on this map

Dose Frequency Randomized Control Trial for Dynamic Temporal and Tactile Cueing (DTTC) Treatment for Childhood Apraxia of Speech

TypeinterventionalSponsorMarquette UniversityRan2023 to 2025Enrolled60ConditionsChildhood Apraxia of SpeechArmsDynamic Temporal and Tactile Cueing Treatment
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Jenya Iuzzini-SeigelDepartment of Speech Pathology and Audiology, Marquette University, PO Box 1881, Harriet Barker Cramer Hall, Milwaukee, WI, 53201, USA. jenya.iuzzini-seigel@marquette.edu.
Julie CaseSpeech-Language-Hearing Sciences, Hofstra University, Davison Hall 106B, 110, Hempstead, NY, 11549, USA.
Maria I GrigosCommunicative Sciences and Disorders, New York University, 665 Broadway, 9th floor, New York, NY, 10012, USA.
Shelley L VellemanUniversity of Vermont, Pomeroy Hall, 489 Main St, Burlington, VT, 05405, USA.
Donna ThomasUniversity of Sydney, Susan Wakil Health Building, Western Avenue, Camperdown, NSW, 2006, Australia.
Elizabeth MurrayUniversity of Sydney, Susan Wakil Health Building, Western Avenue, Camperdown, NSW, 2006, Australia.
University of Sydney · AUHofstra University · USMarquette University · USNew York University · USUniversity of Vermont · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildhood apraxia of speech (CAS) is a pediatric motor-based speech sound disorder that requires a specialized approach to intervention. The extant literature on the treatment of CAS commonly recommends intensive treatment using a motor-based approach, with some of the best evidence supporting the use of Dynamic Temporal and Tactile Cueing (DTTC). To date, a rigorous and systematic comparison of high and low dose frequency (i.e., frequency of therapy sessions) has not been undertaken for DTTC, resulting in a lack of evidence to guide decisions about the optimal treatment schedule for this intervention. The current study aims to fill this gap in knowledge by comparing treatment outcomes when dose frequency is varied.

methodsA randomized controlled trial will be conducted to examine the efficacy of low versus high dose frequency on DTTC treatment outcomes in children with CAS. A target of 60 children, 2;6-7;11 years of age, will be recruited to participate in this study. Treatment will be provided in the community setting by speech-language pathologists who have completed specialized training administering DTTC in a research reliable manner. True randomization with concealed allocation will be used to assign children to either the low or high dose frequency group. Treatment will be administered in 1-h sessions either 4 times per week over a 6-week period (high dose) or 2 times per week over a 12-week period (low dose). To measure treatment gains, probe data will be collected before treatment, during treatment, and 1 day, 1 week, 4 weeks, and 12 weeks post-treatment. Probe data will consist of customized treated words and a standard set of untreated words to assess generalization of treatment gains. The primary outcome variable will be whole word accuracy, encompassing segmental, phonotactic, and suprasegmental accuracy. DISCUSSION: This will be the first randomized controlled trial to evaluate dose frequency for DTTC treatment in children with CAS.

trial registrationClinicalTrials.gov identifier NCT05675306, January 6, 2023.

Indexed as

ApraxiasLanguage Development DisordersChildCuesHumansRandomized Controlled Trials as TopicSoundSpeechChildhood apraxia of speechDose frequencyDTTCMotor speechRandomized controlled trialTreatmentTreatment schedule

Identifiers

PMID37226208
PMCPMC10208915
OpenAlexW4378172425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.