Evidence map›Paper›PMID 37225996›Full record

ArticleNature2023

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

Alexis González, Adriana Covarrubias-Pinto, Ramachandra M Bhaskara, Marius Glogger, Santosh K Kuncha, Audrey Xavier, Eric Seemann, Mohit Misra, Marina E Hoffmann, Bastian Bräuning and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
31.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 151 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Regulation and roles of mammalian mitophagy.Nature reviews. Molecular cell biology · 2026
    Review
  10. Selective autophagy in kidney health and disease.Nature reviews. Nephrology · 2026
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. The ATG14: multi-layer autophagy control and an emerging therapeutic target in cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Alexis González *Institute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0003-3741-6854
Adriana Covarrubias-Pinto *Institute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0002-8946-2804
Ramachandra M BhaskaraInstitute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0002-7742-0391
Marius GloggerInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.ORCID 0000-0003-2834-2785
Santosh K KunchaInstitute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0002-2538-8342
Audrey XavierInstitute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.
Eric SeemannInstitute of Biochemistry I, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-3270-1253
Mohit MisraInstitute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.
Marina E HoffmannInstitute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany.ORCID 0000-0002-5381-3043
Bastian BräuningDepartment of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.
Ashwin BalakrishnanInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.ORCID 0000-0003-4059-8345
Britta QualmannInstitute of Biochemistry I, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0002-5743-5764
Volker DötschInstitute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Goethe University Frankfurt, Frankfurt, Germany.ORCID 0000-0001-5720-212X
Brenda A SchulmanDepartment of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.ORCID 0000-0002-3083-1126
Michael M KesselsInstitute of Biochemistry I, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.ORCID 0000-0001-5967-0744
Christian A HübnerInstitute of Human Genetics, University Hospital Jena, Friedrich Schiller University, Jena, Germany.ORCID 0000-0002-1030-4943
Mike HeilemannInstitute of Physical and Theoretical Chemistry, Goethe University Frankfurt, Frankfurt, Germany.ORCID 0000-0002-9821-3578
Gerhard HummerDepartment of Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt am Main, Germany.ORCID 0000-0001-7768-746X
Ivan DikićInstitute of Biochemistry II, Faculty of Medicine, Goethe University Frankfurt, Frankfurt am Main, Germany. dikic@biochem2.uni-frankfurt.de.ORCID 0000-0001-8156-9511
Goethe University Frankfurt · DEJena University Hospital · DEMax Planck Institute of Biochemistry · DEFriedrich Schiller University Jena · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endoplasmic reticulum (ER) undergoes continuous remodelling via a selective autophagy pathway, known as ER-phagy

Indexed as

AutophagyEndoplasmic ReticulumEndoplasmic Reticulum StressUbiquitinationIntracellular Signaling Peptides and ProteinsMicrotubule-Associated ProteinsReceptors, Autocrine Motility FactorUbiquitinsIntracellular Signaling Peptides and ProteinsMicrotubule-Associated ProteinsReceptors, Autocrine Motility FactorUbiquitins

Identifiers

PMID37225996
PMCPMC10247366
OpenAlexW4378070220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.