Evidence map›Paper›PMID 37225990›Full record

ArticleNature2023

Histone modifications regulate pioneer transcription factor cooperativity.

Kalyan K Sinha, Silvija Bilokapic, Yongming Du, Deepshikha Malik, Mario Halic

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 101 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
  8. A Chromatin Biology Assessment of AlphaFold3.bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
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  18. Article
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  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kalyan K SinhaDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Silvija BilokapicDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0003-2199-2929
Yongming DuDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0001-8015-6037
Deepshikha MalikDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Mario HalicDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. mario.halic@stjude.org.ORCID 0000-0002-0061-7372
St. Jude Children's Research Hospital · US

Funding

Structural and functional studies of chromatin modifiersR01GM135599 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HALIC, MARIO · 2020 to 2023
$1.5M
Chromatin of repetitive elementsR01GM141694 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HALIC, MARIO · 2021 to 2024
$1.4M
NIGMS NIH HHS R01 GM135599NIGMS NIH HHS R01 GM141694
6 · The paper itself

Abstract

Pioneer transcription factors have the ability to access DNA in compacted chromatin

Indexed as

Epigenesis, GeneticHistone CodeHistonesNucleosomesOctamer Transcription Factor-3SOXB1 Transcription FactorsAllosteric RegulationBinding SitesCell DifferentiationChromatin Assembly and DisassemblyCryoelectron MicroscopyDNAHumansMatrilin ProteinsProtein DomainsProtein Processing, Post-TranslationalDNAHistonesLIN28B protein, humanMATN1 protein, humanMatrilin ProteinsNucleosomesOctamer Transcription Factor-3POU5F1 protein, humanRNA-Binding ProteinsSOX2 protein, humanSOXB1 Transcription Factors

Identifiers

PMID37225990
PMCPMC10338341
OpenAlexW4378071676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.