Evidence map›Paper›PMID 37225986›Full record

ArticleNature2023

Structural basis of amine odorant perception by a mammal olfactory receptor.

Lulu Guo, Jie Cheng, Shuo Lian, Qun Liu, Yan Lu, Yuan Zheng, Kongkai Zhu, Minghui Zhang, Yalei Kong, Chao Zhang and 16 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
16.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 83 citations in OpenAlex.

  1. Article
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  11. Exploring LinearJournal of medicinal chemistry · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Deorphanization of Olfactory Trace Amine-Associated Receptors.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 7 institutions in 3 countries.

Lulu Guo *Advanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China.
Jie Cheng *Advanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China.
Shuo Lian *Department of General Surgery, Qilu Hospital of Shandong University, Jinan, China.
Qun Liu *Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Yan Lu *Department of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Yuan Zheng *Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China.
Kongkai Zhu *Advanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China.
Minghui ZhangDepartment of General Surgery, Qilu Hospital of Shandong University, Jinan, China.
Yalei KongSongjiang Institute and Songjiang Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chao ZhangDepartment of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Naikang RongDepartment of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Yuming ZhuangDepartment of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Guoxing FangDepartment of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Jingjing JiangDepartment of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Tianyao ZhangDepartment of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Xiang HanAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China.
Zili LiuDepartment of Biochemistry and Molecular Biology, Shandong University School of Medicine, Jinan, China.
Ming XiaDepartment of Otolaryngology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Shandong, China.
Shangming LiuAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China.
Lei ZhangMOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Physics, Xi'an Jiaotong University, Xi'an, China.ORCID 0000-0002-4880-824X
Stephen D LiberlesHoward Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2177-9741
Xiao YuKey Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology, School of Basic Medical Sciences, Shandong University, Jinan, China.ORCID 0000-0003-1119-8334
Yunfei XuDepartment of General Surgery, Qilu Hospital of Shandong University, Jinan, China. xuyunfei1988@126.com.ORCID 0000-0002-0580-7116
Fan YangAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China. yangfan1357@163.com.ORCID 0000-0002-3000-2336
Qian LiSongjiang Institute and Songjiang Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. liqian@shsmu.edu.cn.ORCID 0000-0003-1300-3377
Jin-Peng SunAdvanced Medical Research Institute, Meili Lake Translational Research Park, Cheeloo College of Medicine, Shandong University, Jinan, China. sunjinpeng@sdu.edu.cn.ORCID 0000-0003-3572-1580
Shandong University · CNQilu Hospital of Shandong University · CNShanghai Jiao Tong University · CNHoward Hughes Medical Institute · USPeking University · CNShandong Provincial Hospital · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Odorants are detected as smell in the nasal epithelium of mammals by two G-protein-coupled receptor families, the odorant receptors and the trace amine-associated receptors

Indexed as

Biogenic AminesOdorantsOlfactory PerceptionPolyaminesReceptors, OdorantAnimalsCryoelectron MicroscopyCyclohexylaminesGTP-Binding Protein alpha SubunitsGTP-Binding Protein alpha Subunits, GsMicePhenethylaminesReceptors, Biogenic AmineSmellSpermidineTrace Amine-Associated ReceptorsBiogenic AminesCyclohexylaminesGTP-Binding Protein alpha SubunitsGTP-Binding Protein alpha Subunits, GsN,N-dimethylcyclohexylamineolfactory G protein subunit alpha olfphenethylaminePhenethylaminesPolyaminesReceptors, Biogenic AmineReceptors, OdorantSpermidineTaar9 protein, mouseTrace Amine-Associated Receptors

Identifiers

PMID37225986
OpenAlexW4377989989

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.