Evidence map›Paper›PMID 37225947›Full record

SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2023

Platelet-rich plasma in chronic Achilles tendinopathy.

Clevio Desouza, Rishabh Dubey, Vijay Shetty

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Efficacy of platelet-rich plasma in grade 2 hamstring muscle injuries: results from a randomized controlled trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Trial
  4. Article
  5. Review
  6. Review
  7. Diagnosis and Management of Common Tendinopathies.Current reviews in musculoskeletal medicine · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Effectiveness of platelet-rich plasma in long-lasting post-viral olfactory dysfunction: a case-series.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  17. Review
  18. Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Clevio DesouzaSaanvi Orthopaedics, 2003, Sorrento High Street, Hiranandani Gardens, Powai, Mumbai, Maharashtra, 400076, India. ceviod@gmail.com.
Rishabh DubeyDR. L.H. Hiranandani Hospital, Powai, Mumbai, Maharashtra, India.
Vijay ShettySaanvi Orthopaedics, 2003, Sorrento High Street, Hiranandani Gardens, Powai, Mumbai, Maharashtra, 400076, India.
Cooper Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAchilles tendinopathy [AT] is a functional problem characterised by swelling and pain above the Achilles tendon insertion region. In individuals with AT, PRP or platelet-rich plasma can be used as an alternative modality of treatment with an aim to lessen the discomfort and enhance functional recovery. We assessed the available data supporting the effectiveness of PRP in treating chronic AT. MATERIALS AND

methodsWe did a literature search for randomised controlled trials [RCTs] that contrasted the effectiveness of PRP with that of eccentric exercise and placebo injections as treatment for AT in databases such as the Cochrane Library, Web of Science, PubMed, and EMBASE. The Visual analogue scale [VAS] score, Victorian Institute of Sports Assessment-Achilles [VISA-A] score, and Achilles tendon thickness were used to measure the results. We used the RevMan 5.3.5 software for statistical analysis.

resultsWe included five RCTs in this meta-analysis. There was no significant difference in the VISA-A between the PRP and placebo groups at 12 weeks, 24 weeks and 1 year after treatment. However, at 6 weeks after treatment, PRP exhibited better efficacy than the placebo treatment. Two studies in our meta-analysis included VAS scores and tendon thickness. There was no significant difference in VAS scores at 6 weeks and 24 weeks after treatment. However, VAS scores at 12 weeks and tendon thickness were significantly different.

conclusionPRP injection is an effective treatment for chronic AT. It has a unique potential for increasing function and reducing discomfort in AT patients.

Indexed as

Achilles TendonMusculoskeletal DiseasesPlatelet-Rich PlasmaSportsTendinopathyHumansInjectionsTreatment OutcomeAchilles tendinopathyPlatelet-rich plasmaRandomised controlled trialTendon thicknessVAS score

Identifiers

PMID37225947
OpenAlexW4377990137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.