Evidence map›Paper›PMID 37225932›Full record

ArticlePaediatric drugs2023

Diagnosis and Management of Pediatric Chronic Hand Eczema: The PeDRA CACHES Survey.

Michael A Haft, Helen H Park, Stephanie S Lee, Jessica M Sprague, Amy S Paller, Colleen H Cotton, Jacob P Thyssen, Lawrence F Eichenfield

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Paediatric drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Michael A HaftDivision of Pediatric and Adolescent Dermatology, Rady Children's Hospital San Diego, 3020 Children's Way, Mail Code 5092, San Diego, CA, 92130, USA.
Helen H ParkDivision of Pediatric and Adolescent Dermatology, Rady Children's Hospital San Diego, 3020 Children's Way, Mail Code 5092, San Diego, CA, 92130, USA.
Stephanie S LeeDivision of Pediatric and Adolescent Dermatology, Rady Children's Hospital San Diego, 3020 Children's Way, Mail Code 5092, San Diego, CA, 92130, USA.
Jessica M SpragueDivision of Pediatric and Adolescent Dermatology, Rady Children's Hospital San Diego, 3020 Children's Way, Mail Code 5092, San Diego, CA, 92130, USA.
Amy S PallerDepartment of Dermatology, Feinberg School of Medicine, Northwestern University, 676 N. St. Clair St. Suite 1600, Chicago, IL, 60611, USA.
Colleen H CottonDivision of Dermatology, Children's National Hospital, 111 Michigan Avenue, NW, Washington, D.C, 20010, USA.
Jacob P ThyssenDepartment of Dermatology, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, DK 2400, Copenhagen, NV, Denmark.
Lawrence F EichenfieldDivision of Pediatric and Adolescent Dermatology, Rady Children's Hospital San Diego, 3020 Children's Way, Mail Code 5092, San Diego, CA, 92130, USA. leichenfield@rchsd.org.ORCID http://orcid.org/0000-0002-2760-0474
University of California San Diego · USChildren's National · USNorthwestern University · USUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic hand eczema (CHE) significantly impacts quality of life. Published literature on pediatric CHE (P-CHE) in North America including knowledge on epidemiology and standard evaluation and management is limited.

objectiveOur objective was to assess diagnostic practices when evaluating patients with P-CHE in the US and Canada, produce data on therapeutic agent prescribing practices for the disorder, and lay the foundation for future studies.

methodsWe surveyed pediatric dermatologists to collect data on clinician and patient population demographics, diagnostic methods, therapeutic agent selection, among other statistics. From June 2021 to January 2022, a survey was distributed to members of the Pediatric Dermatology Research Alliance (PeDRA).

resultsFifty PeDRA members responded stating that they would be interested in participating, and 21 surveys were completed. For patients with P-CHE, providers most often utilize the diagnoses of irritant contact dermatitis, allergic contact dermatitis, dyshidrotic hand eczema, and atopic dermatitis. Contact allergy patch testing and bacterial hand culture are the most used tests for workup. Nearly all utilize topical corticosteroids as first line therapy. Most responders report that they have treated fewer than six patients with systemic agents and prefer dupilumab as first-line systemic therapy.

conclusionsThis is the first characterization of P-CHE among pediatric dermatologists in the United States and Canada. This assessment may prove useful in designing further investigations including prospective studies of P-CHE epidemiology, morphology, nomenclature, and management.

Indexed as

Dermatitis, AtopicDermatologyEczemaChildHumansProspective StudiesQuality of LifeUnited States

Identifiers

PMID37225932
PMCPMC10284996
OpenAlexW4378070537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.