Evidence map›Paper›PMID 37225674›Full record

ReviewJournal of clinical laboratory analysis2023

The role of bacterial infections in rheumatoid arthritis development and novel therapeutic interventions: Focus on oral infections.

Shima Afrasiabi, Nasim Chiniforush, Alireza Partoazar, Ramin Goudarzi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical laboratory analysis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Virtual Probing on the Influence of CaCell biochemistry and biophysics · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Roles of the Caspase-11 Non-Canonical Inflammasome in Rheumatic Diseases.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Shima AfrasiabiLaser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-8341-123X
Nasim ChiniforushLaser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Alireza PartoazarExperimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Ramin GoudarziDivision of Research and Development, Pharmin USA, LLC, San Jose, California, USA.
Laser Research Institute · CNTehran University of Medical Sciences · IRTeikoku Pharma (United States) · US

Funding

Tehran University of Medical Sciences of Medical Science and Health Services 1401-4-209-64414
6 · The paper itself

Abstract

backgroundRheumatoid arthritis (RA) represents a primary public health challenge, which is a major source of pain, disability, and socioeconomic effects worldwide. Several factors contribute to its pathogenesis. Infections are an important concern in RA patients, which play a key role in mortality risk. Despite major advances in the clinical treatment of RA, long-term use of disease-modifying anti-rheumatic drugs can cause serious adverse effects. Therefore, effective strategies for developing novel prevention and RA-modifying therapeutic interventions are sorely needed.

objectiveThis review investigates the available evidence on the interplay between various bacterial infections, particularly oral infections and RA, and focuses on some potential interventions such as probiotics, photodynamic therapy, nanotechnology, and siRNA that can have therapeutic effects.

Indexed as

Arthritis, RheumatoidBacterial InfectionsHumansanti-citrullinated protein antibodies, inflammation, microbiotaimmune dysregulationinfectionsperiodontitisprobiotics, nanoparticles, siRNArheumatoid arthritis

Identifiers

PMID37225674
PMCPMC10290228
OpenAlexW4378070744

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.