Evidence map›Paper›PMID 37225495›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Hereditary Diffuse Gastric Cancer Treated by Prophylactic Total Gastrectomy.

Yasunori Inaba, Kenichi Goda, Masayuki Kondo, Keiichiro Abe, Akira Kanamori, Tsunehiro Suzuki, Keiichi Tominaga, Masatoshi Nakagawa, Shinji Morita, Kazuyuki Kojima and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Risk Factors and Prevention of Stomach Cancer, ExcludingThe Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yasunori InabaDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Kenichi GodaDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Masayuki KondoDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Keiichiro AbeDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Akira KanamoriDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Tsunehiro SuzukiDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Keiichi TominagaDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Masatoshi NakagawaDepartment of Upper Gastrointestinal Surgery, Dokkyo Medical University, Japan.
Shinji MoritaDepartment of Upper Gastrointestinal Surgery, Dokkyo Medical University, Japan.
Kazuyuki KojimaDepartment of Upper Gastrointestinal Surgery, Dokkyo Medical University, Japan.
Kazuyuki IshidaDepartment of Diagnostic Pathology, Dokkyo Medical University, Japan.
Atsushi IrisawaDepartment of Gastroenterology, Dokkyo Medical University, Japan.
Dokkyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a rare case of hereditary diffuse gastric cancer in a Japanese man. A 41-year-old man underwent esophagogastroduodenoscopy which revealed a small gastric erosion. Biopsy specimens showed signet ring cell carcinoma, and endoscopic submucosal dissection was performed. The patient's elder sister had died of gastric cancer at 38 years old. Considering the family history, a genetic test was conducted and revealed a CDH1 germline mutation. Although no carcinomatous lesion was detected endoscopically, prophylactic total gastrectomy was performed. The resection specimen showed seven microlesions of signet ring cell carcinoma confined to the lamina propria mucosae.

Indexed as

AdenocarcinomaCarcinoma, Signet Ring CellStomach NeoplasmsAdultAgedCadherinsGastrectomyGenetic Predisposition to DiseaseGerm-Line MutationHumansMaleCadherinsCDH1endoscopic submucosal dissectionhereditary diffuse gastric cancerprophylactic gastrectomysignet ring cell carcinoma

Identifiers

PMID37225495
PMCPMC10864090
OpenAlexW4377691425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.