Evidence map›Paper›PMID 37225490›Full record

ArticleInternal medicine (Tokyo, Japan)2024

Hepatitis B Virus-related Membranous Nephropathy with Crescentic Formation in an Inactive Carrier of Positive Hepatitis B Surface Antigen with Undetectable DNA under Anti-viral Treatment.

Noriyuki Kounoue, Hideyo Oguchi, Tetuo Mikami, Yutaka Yamaguchi, Akinori Hashiguchi, Hidenari Nagai, Kaori Watanabe, Satoshi Furukawa, Kana Hisamatsu, Ken Sakai

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. [A case of decompensated hepatitis B virus-related cirrhosis combined with renal injury rescue treatment using tenofovir amibufenamide tablet].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Noriyuki KounoueDepartment of Nephrology, Toho University Faculty of Medicine, Japan.
Hideyo OguchiDepartment of Nephrology, Toho University Faculty of Medicine, Japan.
Tetuo MikamiDepartment of Pathology, Toho University Faculty of Medicine, Japan.
Yutaka YamaguchiYamaguchi's Pathology Laboratory, Japan.
Akinori HashiguchiDepartment of Pathology, Keio University School of Medicine, Japan.
Hidenari NagaiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Faculty of Medicine, Japan.
Kaori WatanabeDepartment of Nephrology, Toho University Faculty of Medicine, Japan.
Satoshi FurukawaDepartment of Nephrology, Toho University Faculty of Medicine, Japan.
Kana HisamatsuDepartment of Nephrology, Toho University Faculty of Medicine, Japan.
Ken SakaiDepartment of Nephrology, Toho University Faculty of Medicine, Japan.
Toho University · JPKeio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man who was an inactive hepatitis B virus (HBV) carrier with positive hepatitis B surface antigen (HBs antigen) and undetectable HBV-DNA under anti-viral treatment developed nephrotic syndrome at 52 years old, and a renal biopsy revealed advanced membranous nephropathy (MN) with focal cellular crescents, interstitial hemorrhaging, and peritubular capillaritis. Immunofluorescence studies demonstrated granular IgG deposition and HBs antigen-positivity along the capillaries. Glomeruli were negative for phospholipase A2 receptor 1. There were no clinical findings of systemic vasculitis. We considered MN combined with small-vessel vasculitis due to HBV infection. These results suggest that HBV-related kidney disease should be considered even in patients with an inactive HBV carrier status under treatment.

Indexed as

Glomerulonephritis, MembranousHepatitis BAntiviral AgentsDNAHepatitis B Surface AntigensHepatitis B virusHumansMaleMiddle AgedAntiviral AgentsDNAHepatitis B Surface Antigenscase reporthepatitis B virushepatitis B virus-related membranous nephropathyinactive carriermembranous nephropathy

Identifiers

PMID37225490
PMCPMC10824637
OpenAlexW4377691722

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.