Evidence map›Paper›PMID 37225246›Full record

ArticleCanadian journal of surgery. Journal canadien de chirurgie

Clinical characteristics of SARS-CoV-2 vaccine-related acute appendicitis.

Elchanan Quint, Ivan Kukeev, Itai Hazan, Daniel Grupel, Oleg Dukhno, Anton Osyntsov, Gilbert Sebbag, Ohad Guetta, David Czeiger

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian journal of surgery. Journal canadien de chirurgie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Acute abdomen following COVID-19 vaccination: a systematic review.Clinical and experimental vaccine research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Elchanan QuintDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel) elchananq@gmail.com.
Ivan KukeevDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
Itai HazanDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
Daniel GrupelDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
Oleg DukhnoDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
Anton OsyntsovDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
Gilbert SebbagDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
Ohad GuettaDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
David CzeigerDepartment of General Surgery B, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Israel (Quint, Kukeev, Dukhno, Osyntsov, Sebbag, Guetta, Czeiger); Clinical Research Center, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel (Hazan); Internal Medicine B, Soroka University Medical Center, Ben Gurion University of the Negev, Faculty of Health Sciences, Beer Sheva, Israel (Grupel).
Ben-Gurion University of the Negev · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn a large nationwide mass vaccination setting, the SARS-CoV-2 vaccine was recently linked to myocarditis, lymphadenopathy, herpes zoster infection and appendicitis. We aimed to examine the characteristics and management of SARS-CoV-2 vaccine-related acute appendicitis.

methodsWe performed a retrospective cohort study in a large tertiary medical centre in Israel. All patients presenting with acute appendicitis within 21 days of receiving their SARS-CoV-2 vaccination (PCVAA group) were compared with patients who presented with acute appendicitis not related to the vaccination (N-PCVAA group).

resultsWe reviewed the records of 421 patients with acute appendicitis from December 2020 to September 2021; 38 (9%) patients presented with acute appendicitis within 21 days of receiving their SARS-CoV-2 vaccination. Patients in the PCVAA group were older than those in the N-PCVAA group (mean 41 ± 19 yr v. 33 ± 15 yr, respectively,

conclusionWith the exception of older age, the clinical characteristics of patients presenting with acute appendicitis within 21 days of receiving the SARS-CoV-2 vaccination did not differ from those of patients who presented with acute appendicitis not related to the vaccination. This finding suggests that vaccine-related acute appendicitis is similar to "classic" acute appendicitis.

Indexed as

AppendicitisCOVID-19COVID-19 VaccinesAcute DiseaseFemaleHumansMaleRetrospective StudiesSARS-CoV-2COVID-19 Vaccines

Identifiers

PMID37225246
PMCPMC10228661
OpenAlexW4378172920

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.