Evidence map›Paper›PMID 37224793›Full record

Trial reportGynecologic oncology2023

Endometrial cancer survivors' perceptions of their cardiovascular disease risk (results from WF-1804CD AH-HA).

Joseph A DeMari, Emily V Dressler, Randi E Foraker, Brian J Wells, Sydney Smith, Heidi Klepin, William G Hundley, Glenn J Lesser, David I Shalowitz, Chandylen L Nightingale and 2 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Gynecologic oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03935282 (Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03935282 nacompletednot on this map

Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors (AH-HA)

TypeinterventionalSponsorWake Forest University Health SciencesRan2020 to 2025Enrolled645ConditionsBreast Neoplasm, Prostatic Neoplasm, Colorectal Neoplasms, Endometrial NeoplasmsArmsAH-HA Tool in the EPIC EHR
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Observational
  4. Article
  5. [Causal Relationship Between Components of Metabolic Syndrome and Endometrial Carcinoma].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Joseph A DeMariSection on Gynecologic Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America. Electronic address: jdemari@wakehealth.edu.
Emily V DresslerDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.
Randi E ForakerDepartment of Medicine, Washington University in St. Louis School of Medicine, St Louis, MO, United States of America.
Brian J WellsDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.
Sydney SmithDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.
Heidi KlepinSection on Hematology-Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
William G HundleyDivision of Cardiology, Pauley Heart Center, Virginia Commonwealth University, Richmond, VA, United States.
Glenn J LesserSection on Hematology-Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, United States.
David I ShalowitzSection on Gynecologic Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.
Chandylen L NightingaleDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.
Marcia HernandezDepartment of Women's Oncology, Mercy Hospital, Springfield, MO, United States of America.
Kathryn E WeaverDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, United States of America.

Funding

Wake Forest NCORP Research BaseUG1CA189824 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Emily Van Meter Dressler, GLENN J LESSER · 2014 to 2026
$57.9M
Extending Automated Heart Health Assessment (AH-HA) for Cancer Survivors to Expand Provider and Patient Reach and Promote SustainabilityR01CA226078 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI RANDI E FORAKER, Kathryn Elizabeth Weaver · 2018 to 2026
$3.3M
NCI NIH HHS R01 CA226078NCI NIH HHS UG1 CA189824
6 · The paper itself

Abstract

objectiveDespite considerable burden of cardiovascular disease (CVD), data on endometrial cancer survivors' CVD perceptions are lacking. We assessed survivors' perspectives on addressing CVD risk during oncology care.

methodsThis cross-sectional analysis utilized data from an ongoing trial of an EHR heart health tool (R01CA226078 & UG1CA189824) conducted through the NCI Community Oncology Research Program (NCORP, WF-1804CD). Endometrial cancer survivors post-potentially curative treatment were recruited from community practices and completed a pre-visit baseline survey, including American Heart Association Simple 7 CVD factors. Likert-type questions assessed confidence in understanding CVD risk, CVD risk perception, and desired discussion during oncology care. Medical record abstraction ascertained data on CVD and cancer characteristics.

resultsSurvivors (N = 55, median age = 62; 62% 0-2 years post-diagnosis) were predominately white, non-Hispanic (87%). Most agreed/strongly agreed heart disease poses a risk to their health (87%) and oncology providers should talk to patients about heart health (76%). Few survivors reported smoking (12%) but many had poor/intermediate values for blood pressure (95%), body mass index (93%), fasting glucose/A1c (60%), diet (60%), exercise (47%) and total cholesterol (53%). 16% had not seen a PCP in the last year; these survivors were more likely to report financial hardship (22% vs 0%; p = 0.02). Most reported readiness to take steps to maintain or improve heart health (84%).

conclusionsDiscussions of CVD risk during routine oncology care are likely to be well received by endometrial cancer survivors. Strategies are needed to implement CVD risk assessment guidelines and to enhance communication and referrals with primary care. Clinical Trials #: NCT03935282.

Indexed as

Cancer SurvivorsCardiovascular DiseasesEndometrial NeoplasmsNeoplasmsCross-Sectional StudiesFemaleHumansMiddle AgedSurvivorsCardiovascular diseaseEndometrial cancerSurvivorship

Identifiers

PMID37224793
PMCPMC10330616

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.