Evidence map›Paper›PMID 37224244›Full record

ArticleScience advances2023

Proteomic identification of beer brewing products in the ground layer of Danish Golden Age paintings.

Fabiana Di Gianvincenzo, Cecil Krarup Andersen, Troels Filtenborg, Meaghan Mackie, Madeleine Ernst, Jazmín Ramos Madrigal, Jesper V Olsen, Jørgen Wadum, Enrico Cappellini

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
8.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Fabiana Di GianvincenzoGlobe Institute, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.ORCID 0000-0003-3304-0749
Cecil Krarup AndersenRoyal Danish Academy, Conservation, Philip De Langes Allé 10, 3.15, 1435 Copenhagen, Denmark.ORCID 0000-0002-3823-5812
Troels FiltenborgNational Gallery of Denmark, Sølvgade 48-50, 1307 Copenhagen, Denmark.
Meaghan MackieGlobe Institute, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.ORCID 0000-0003-0763-7592
Madeleine ErnstSection for Clinical Mass Spectrometry, Danish Center for Neonatal Screening, Department of Congenital Disorders, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen, Denmark.ORCID 0000-0001-9530-3837
Jazmín Ramos MadrigalGlobe Institute, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.ORCID 0000-0002-1661-7991
Jesper V OlsenProteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.ORCID 0000-0002-4747-4938
Jørgen WadumCentre for Art Technological Studies and Conservation, National Gallery of Denmark, Sølvgade 48-50, 1307 Copenhagen, Denmark.ORCID 0000-0002-7215-5509
Enrico CappelliniGlobe Institute, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.ORCID 0000-0001-7885-7811
University of Copenhagen · DKDanish Technological Institute · DKNational Gallery of Denmark · DKSchools of Visual Arts, The Royal Danish Academy of Fine Arts · DKStatens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of mass spectrometry-based proteomics to artworks provides accurate and detailed characterization of protein-based materials used in their production. This is highly valuable to plan conservation strategies and reconstruct the artwork's history. In this work, the proteomic analysis of canvas paintings from the Danish Golden Age led to the confident identification of cereal and yeast proteins in the ground layer. This proteomic profile points to a (by-)product of beer brewing, in agreement with local artists' manuals. The use of this unconventional binder can be connected to the workshops within the Royal Danish Academy of Fine Arts. The mass spectrometric dataset generated from proteomics was also processed with a metabolomics workflow. The spectral matches observed supported the proteomic conclusions, and, in at least one sample, suggested the use of drying oils. These results highlight the value of untargeted proteomics in heritage science, correlating unconventional artistic materials with local culture and practices.

Indexed as

PaintingsBeerDenmarkEdible GrainProteomics

Identifiers

PMID37224244
PMCPMC10208569
OpenAlexW4378070568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.