ArticleScience advances2023
Balancing economic and epidemiological interventions in the early stages of pathogen emergence.
Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Premature termination of unemployment benefits increased COVID-19 transmission and deaths in the USA.Nature human behaviour · 2026Article
- Improving policy design and epidemic response using integrated models of economic choice and disease dynamics with behavioral feedback.PLoS computational biology · 2025Article
- Estimation of end-of-outbreak probabilities in the presence of delayed and incomplete case reporting.Proceedings. Biological sciences · 2025Article
- Fine-tuning the evolutionary stability of recombinant herpesviral transmissible vaccines.Proceedings. Biological sciences · 2024Article
- An Ultra-Compact and Low-Cost LAMP-Based Virus Detection Device.Sensors (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global pandemic of COVID-19 has underlined the need for more coordinated responses to emergent pathogens. These responses need to balance epidemic control in ways that concomitantly minimize hospitalizations and economic damages. We develop a hybrid economic-epidemiological modeling framework that allows us to examine the interaction between economic and health impacts over the first period of pathogen emergence when lockdown, testing, and isolation are the only means of containing the epidemic. This operational mathematical setting allows us to determine the optimal policy interventions under a variety of scenarios that might prevail in the first period of a large-scale epidemic outbreak. Combining testing with isolation emerges as a more effective policy than lockdowns, substantially reducing deaths and the number of infected hosts, at lower economic cost. If a lockdown is put in place early in the course of the epidemic, it always dominates the "laissez-faire" policy of doing nothing.
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