Evidence map›Paper›PMID 37224136›Full record

ArticlePloS one2023

Acute clinical and financial outcomes of esophagectomy at safety-net hospitals in the United States.

Sara Sakowitz, Russyan Mark Mabeza, Syed Shahyan Bakhtiyar, Arjun Verma, Shayan Ebrahimian, Amulya Vadlakonda, Sha'shonda Revels, Peyman Benharash

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sara SakowitzCardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, CA, United States of America.ORCID 0009-0004-7318-7571
Russyan Mark MabezaCardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, CA, United States of America.ORCID 0000-0001-7910-1629
Syed Shahyan BakhtiyarCardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, CA, United States of America.
Arjun VermaCardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, CA, United States of America.
Shayan EbrahimianCardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, CA, United States of America.ORCID 0000-0002-6819-4871
Amulya VadlakondaCardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, CA, United States of America.ORCID 0000-0003-3778-1966
Sha'shonda RevelsDepartment of Surgery, University of California, Los Angeles, CA, United States of America.
Peyman BenharashCardiovascular Outcomes Research Laboratories (CORELAB), University of California, Los Angeles, CA, United States of America.ORCID 0000-0002-4705-0262
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile safety-net hospitals (SNH) play a critical role in the care of underserved communities, they have been associated with inferior postoperative outcomes. This study evaluated the association of hospital safety-net status with clinical and financial outcomes following esophagectomy.

methodsAll adults (≥18 years) undergoing elective esophagectomy for benign and malignant gastroesophageal disease were identified in the 2010-2019 Nationwide Readmissions Database. Centers in the highest quartile for the proportion of uninsured/Medicaid patients were classified as SNH (others: non-SNH). Regression models were developed to evaluate adjusted associations between SNH status and outcomes, including in-hospital mortality, perioperative complications, and resource use. Royston-Parmar flexible parametric models were used to assess time-varying hazard of non-elective readmission over 90 days.

resultsOf an estimated 51,649 esophagectomy hospitalizations, 9,024 (17.4%) were performed at SNH. While SNH patients less frequently suffered from gastroesophageal malignancies (73.2 vs 79.6%, p<0.001) compared to non-SNH, the distribution of age and comorbidities were similar. SNH was independently associated with mortality (AOR 1.24, 95% CI 1.03-1.50), intraoperative complications (AOR 1.45, 95% CI 1.20-1.74) and need for blood transfusions (AOR 1.61, 95% CI 1.35-1.93). Management at SNH was also associated with incremental increases in LOS (+1.37, 95% CI 0.64-2.10), costs (+10,400, 95% CI 6,900-14,000), and odds of 90-day non-elective readmission (AOR 1.11, 95% CI 1.00-1.23).

conclusionsCare at safety-net hospitals was associated with higher odds of in-hospital mortality, perioperative complications, and non-elective rehospitalization following elective esophagectomy. Efforts to provide sufficient resources at SNH may serve to reduce complications and overall costs for this procedure.

Indexed as

EsophagectomySafety-net ProvidersAdultDatabases, FactualHospitalizationHospital MortalityHumansSyndromeUnited States

Identifiers

PMID37224136
PMCPMC10208475
OpenAlexW4378070577

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.