Evidence map›Paper›PMID 37223747›Full record

ArticlemicroLife2023

Revealing the small proteome of

Lydia Hadjeras, Jürgen Bartel, Lisa-Katharina Maier, Sandra Maaß, Verena Vogel, Sarah L Svensson, Florian Eggenhofer, Rick Gelhausen, Teresa Müller, Omer S Alkhnbashi and 4 more

Open access · goldAbstract read
In one paragraph

Article in microLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. HThe FEBS journal · 2026
    Article
  2. Identification and Characterization of Microproteins/ MicroORFs.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
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  8. Article
  9. Journal of bacteriology · 2025
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Provirus deletion frommicroLife · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Lydia HadjerasDepartment of Molecular Infection Biology II, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2 / D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0003-4645-8044
Jürgen BartelDepartment of Microbial Proteomics, Institute of Microbiology, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany.ORCID https://orcid.org/0000-0001-9781-8156
Lisa-Katharina MaierBiology II, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID https://orcid.org/0000-0001-5834-9035
Sandra MaaßDepartment of Microbial Proteomics, Institute of Microbiology, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany.ORCID https://orcid.org/0000-0002-6573-1088
Verena VogelBiology II, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Sarah L SvenssonDepartment of Molecular Infection Biology II, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2 / D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0002-3183-6084
Florian EggenhoferBioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.ORCID https://orcid.org/0000-0001-9564-7525
Rick GelhausenBioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.ORCID https://orcid.org/0000-0003-4161-4394
Teresa MüllerBioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.ORCID https://orcid.org/0000-0003-1252-9684
Omer S AlkhnbashiInformation and Computer Science Department, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia.ORCID https://orcid.org/0000-0001-8088-590X
Rolf BackofenBioinformatics Group, Department of Computer Science, University of Freiburg, Georges-Koehler-Allee 106, 79110 Freiburg, Germany.ORCID https://orcid.org/0000-0001-8231-3323
Dörte BecherDepartment of Microbial Proteomics, Institute of Microbiology, University of Greifswald, Felix-Hausdorff-Str. 8, 17489 Greifswald, Germany.ORCID https://orcid.org/0000-0002-9630-5735
Cynthia M SharmaDepartment of Molecular Infection Biology II, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2 / D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0002-2321-9705
Anita MarchfelderBiology II, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID https://orcid.org/0000-0002-1382-1794
University of Freiburg · DEUniversität Greifswald · DEUniversität Ulm · DEUniversity of Würzburg · DEKing Fahd University of Petroleum and Minerals · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In contrast to extensively studied prokaryotic 'small' transcriptomes (encompassing all small noncoding RNAs), small proteomes (here defined as including proteins ≤70 aa) are only now entering the limelight. The absence of a complete small protein catalogue in most prokaryotes precludes our understanding of how these molecules affect physiology. So far, archaeal genomes have not yet been analyzed broadly with a dedicated focus on small proteins. Here, we present a combinatorial approach, integrating experimental data from small protein-optimized mass spectrometry (MS) and ribosome profiling (Ribo-seq), to generate a high confidence inventory of small proteins in the model archaeon

Indexed as

archaeaHaloferax volcaniimass spectrometryproteomicsRibo-seqribosome profilingsmall proteinsmall proteomesORFsprotein

Identifiers

PMID37223747
PMCPMC10117724
OpenAlexW4317037169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.