Evidence map›Paper›PMID 37223527›Full record

ReviewGenes & diseases2023

Oncolytic viruses: A novel treatment strategy for breast cancer.

Mohammad Javanbakht, Sanaz Tahmasebzadeh, Luca Cegolon, Nasrin Gholami, Mandana Kashaki, Hassan Nikoueinejad, Mohamad Mozafari, Mahsa Mozaffari, Shi Zhao, Mostafa Khafaei and 3 more

Abstract readReview
In one paragraph

Review in Genes & diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Oncolytic viruses: advanced strategies in cancer therapy.Signal transduction and targeted therapy · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Breast cancer immunotherapy: a comprehensive review.Clinical and experimental medicine · 2023
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mohammad JavanbakhtNephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran 1435916471, Iran.
Sanaz TahmasebzadehMehrestan Health Network, Iranshahr University of Medical Sciences, Iranshahr 9966118984, Iran.
Luca CegolonUniversity of Trieste, Department of Medical, Surgical & Health Sciences, Trieste 34128, Italy.
Nasrin GholamiHematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz 5167956561, Iran.
Mandana KashakiShahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Sciences (IUMS), Tehran 1997673144, Iran.
Hassan NikoueinejadNephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, Tehran 1435916471, Iran.
Mohamad MozafariDepartment of General Surgery, Urmia University of Medical Science, Urmia 57147, Iran.
Mahsa MozaffariDepartment of Pediatrics, Iran University of Medical Sciences, Tehran 1449614535, Iran.
Shi ZhaoJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong Special Administrative Region 999077, China.
Mostafa KhafaeiHuman Genetics Research Center, Baqiyatallah University of Medical Sciences, Tehran 169875931, Iran.
Morteza IzadiHealth Research Center, Baqiyatallah University of Medical Sciences, Tehran 1435916471, Iran.
Saeid FathiRazi Vaccine and Serum Research Institute, Agriculture Research, Education and Extension Organization (AREEO), Karaj 11365-1558, Iran.
Reza Akhavan-SigariDepartment of Neurosurgery, University Medical Center, Tuebingen 72076, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer, an unceasingly occurring neoplasm, is one of the major determinants of mortality in women. Several ineffective attempts have been pursued using with conventional therapies against breast cancer. Resistance to existing therapies and their respective debilitating adverse effects have led research toward a new era of cancer treatment using viruses. Virotherapy constitutes a developing treatment modality with multiple mechanisms of therapeutic activity in which the viruses can be directly oncolyticand can express transgenes or induce host immune response against tumor cells. Several different DNA- and RNA-containing viruses have been considered for virotherapy of breast cancer including adenovirus, herpes virus, vaccinia, reovirus, Newcastle Disease virus, measles virus and vesicular stomatitis virus. This review aims to summarize the viro-therapeutical agents against breast malignancies. Key Scientific Concepts of Review: In this review paper, we proposed a new strategy to virus's combinatorial treatments using several kinds of transgenes and drugs. These recombinant viruses have provided evidence of treatment efficacy against human breast cancer.

Indexed as

AdenovirusBreast cancerHerpes virusMeasles virusNewcastle disease virusReovirusVacciniaVesicular stomatitis virusVirotherapy

Identifiers

PMID37223527
PMCPMC10201557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.