Evidence map›Paper›PMID 37223255›Full record

ArticlemicroLife2021

The composition and function of

Irina Afonina, Brenda Tien, Zeus Nair, Artur Matysik, Ling Ning Lam, Mark Veleba, Augustine Koh Jing Jie, Rafi Rashid, Amaury Cazenave-Gassiot, Marcus Wenk and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in microLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Microbiology (Reading, England) · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Membrane Vesicles of Clostridioides difficile and Other Clostridial Species.Advances in experimental medicine and biology · 2024
    Article
  14. Enterococcal Membrane Vesicles as Vaccine Candidates.International journal of molecular sciences · 2023
    Article
  15. Discovery of phosphorylated lantibiotics with proimmune activity that regulate the oral microbiome.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Article
  17. Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance.International journal of molecular sciences · 2022
    Review
  18. Review
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Irina AfoninaSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Brenda TienSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Zeus NairSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.ORCID https://orcid.org/0000-0001-9662-4958
Artur MatysikSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Ling Ning LamSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Mark VelebaSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.
Augustine Koh Jing JieSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.ORCID https://orcid.org/0000-0002-2032-0867
Rafi RashidSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.ORCID https://orcid.org/0000-0003-0737-9116
Amaury Cazenave-GassiotSingapore Lipidomics Incubator, National University of Singapore, 28 Medical Dr, Singapore 117456.ORCID https://orcid.org/0000-0002-3050-634X
Marcus WenkSingapore Lipidomics Incubator, National University of Singapore, 28 Medical Dr, Singapore 117456.
Sun Nyunt WaiUmeå Centre for Microbial Research (UCMR), Department of Molecular Biology, Umeå University, 90187 Umeå, Sweden.
Kimberly A KlineSingapore Centre for Environmental Life Science Engineering, Nanyang Technological University, 60 Nanyang Drive, 637551, Singapore.ORCID https://orcid.org/0000-0002-5472-3074
Nanyang Technological University · SGNational University of Singapore · SGUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membrane vesicles (MVs) contribute to various biological processes in bacteria, including virulence factor delivery, antimicrobial resistance, host immune evasion and cross-species communication. MVs are frequently released from the surface of both Gram-negative and Gram-positive bacteria during growth. In some Gram-positive bacteria, genes affecting MV biogenesis have been identified, but the mechanism of MV formation is unknown. In

Indexed as

Enterococcus faecalishorizontal gene transferlipidomicsmembrane vesiclesNF-kB signalingproteomics

Identifiers

PMID37223255
PMCPMC10117786
OpenAlexW3155237425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.