Evidence map›Paper›PMID 37223250›Full record

ArticlemicroLife2021

Grad-seq identifies KhpB as a global RNA-binding protein in

Vanessa Lamm-Schmidt, Manuela Fuchs, Johannes Sulzer, Milan Gerovac, Jens Hör, Petra Dersch, Jörg Vogel, Franziska Faber

Open access · goldAbstract read
In one paragraph

Article in microLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 50 citations in OpenAlex.

  1. Molecular genetic characterization of bacterial KH-domain proteins.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Inactivation of KhpB (EloR/Jag) inApplied and environmental microbiology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. What makes a small RNA work?Nucleic acids research · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Vanessa Lamm-SchmidtFaculty of Medicine, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2/D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0003-4281-8006
Manuela FuchsFaculty of Medicine, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2/D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0002-7804-1959
Johannes SulzerFaculty of Medicine, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2/D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0002-2800-9328
Milan GerovacFaculty of Medicine, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2/D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0002-6929-7178
Jens HörFaculty of Medicine, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2/D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0003-3052-4430
Petra DerschCentre for Molecular Biology of Inflammation, Institute for Infectiology, University of Münster, Von-Esmarch-Straße 56, 48149 Münster, Germany.ORCID https://orcid.org/0000-0001-8177-3280
Jörg VogelFaculty of Medicine, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2/D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0003-2220-1404
Franziska FaberFaculty of Medicine, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Josef-Schneider-Straße 2/D15, 97080 Würzburg, Germany.ORCID https://orcid.org/0000-0002-8700-6522
University of Würzburg · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Much of our current knowledge about cellular RNA-protein complexes in bacteria is derived from analyses in gram-negative model organisms, with the discovery of RNA-binding proteins (RBPs) generally lagging behind in Gram-positive species. Here, we have applied Grad-seq analysis of native RNA-protein complexes to a major Gram-positive human pathogen,

Indexed as

Clostridioides difficileGrad-seqJagKhpAKhpBRNA-binding proteinsmall RNAtoxin

Identifiers

PMID37223250
PMCPMC10117727
OpenAlexW3159645530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.