Evidence map›Paper›PMID 37222940›Full record

ArticleVeterinary research communications2023

Production and characterization of monoclonal antibodies against foot-and-mouth disease virus serotype O and development of a sandwich ELISA for virus antigen detection.

Smrutirekha Mallick, Rabindra Prasad Singh, Jitendra Kumar Biswal, Jajati Keshari Mohapatra, Manoranjan Rout, Reshma Samanta, Sagar Ashok Khulape, Rajeev Ranjan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary research communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Smrutirekha MallickICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India. drsmrutirekhamallick@gmail.com.
Rabindra Prasad SinghICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India.
Jitendra Kumar BiswalICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India.
Jajati Keshari MohapatraICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India.
Manoranjan RoutICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India.
Reshma SamantaICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India.
Sagar Ashok KhulapeICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India.
Rajeev RanjanICAR-Directorate of Foot and Mouth Disease-International Centre for FMD, Bhubaneswar, Khordha, Odisha, 752050, India.
Project Directorate on Foot and Mouth Disease · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foot-and-mouth disease (FMD) is endemic in India with a majority of outbreaks caused by FMD virus (FMDV) serotype O. In the present study a panel of eight (2F9, 2G10, 3B9, 3H5, 4C8, 4D6, 4G10 and 5B6) mouse monoclonal antibodies (MAbs) were developed against FMDV serotype O Indian vaccine strain, O/IND/R2/75 via hybridoma systems. The MAbs generated were FMDV/O specific without cross-reactivity against FMDV type A and Asia 1. All the MAbs were identified as IgG1/kappa type. Out of eight, three MAbs (3B9, 3H5 and 4G10) demonstrated virus neutralizing activity. The reactivity of all MAbs increased with heat treated (@56

Indexed as

Foot-and-Mouth DiseaseFoot-and-Mouth Disease VirusVaccinesAnimalsAntibodies, MonoclonalAntibodies, ViralEnzyme-Linked Immunosorbent AssayMiceO AntigensRabbitsSerogroupAntibodies, MonoclonalAntibodies, ViralO AntigensVaccinesAntigen detectionFoot-and-mouth disease virusMonoclonal antibodySandwich ELISASerotype O

Identifiers

PMID37222940
PMCPMC10206340
OpenAlexW4377939670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.