Evidence map›Paper›PMID 37222797›Full record

ArticleLangenbeck's archives of surgery2023

Comparison of functional and oncological outcome of conformal sphincter preservation operation, low anterior resection, and abdominoperineal resection in very low rectal cancer: a retrospective comparative cohort study with propensity score matching.

Ge Sun, Zheng Lou, Kuo Zheng, Yuntao Chen, Hang Zhang, Rongbo Wen, Xianhua Gao, Ronggui Meng, Haifeng Gong, Chenguang Bai and 2 more

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In one paragraph

Article in Langenbeck's archives of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Ge Sun *Department of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Zheng Lou *Department of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Kuo ZhengDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Yuntao ChenDepartment of Epidemiology and Public Health, University College London, London, UK.
Hang ZhangDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Rongbo WenDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Xianhua GaoDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Ronggui MengDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Haifeng GongDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.
Chenguang BaiDepartment of Pathology, Changhai Hospital, Shanghai, China.
Edgar J B FurnéeDepartment of Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Wei ZhangDepartment of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China. weizhang2000cn@163.com.ORCID https://orcid.org/0000-0003-3094-9711
Second Military Medical University · CNUniversity Medical Center Groningen · NLUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeConformal sphincter preservation operation (CSPO) procedure is a sphincter preservation procedure for preserving the anal canal function for very low rectal cancers. This study investigated the functional and oncological outcome of conformal sphincter preservation operation by comparing with low anterior resection (LAR) and abdominoperineal resection (APR).

methodsThis is a retrospective comparative study. Patients who received conformal sphincter preservation operation (n = 52), low anterior resection (n = 54), or abdominoperineal resection (n = 69) were included between 2011 and 2016 in a tertiary referral hospital. Propensity score matching was applied to adjust the baseline characteristics which may influence the choice of the surgical procedure.

resultsTwenty-one pairs of conformal sphincter preservation operation vs. low anterior resection and 29 pairs of conformal sphincter preservation operation vs. abdominoperineal resection were selected. The first group had a higher tumor location than the second group. Compared with the low anterior resection group, the conformal sphincter preservation operation group had shorter distal resection margins; however, no significant differences were identified in daily stool frequency, Wexner incontinence score, local recurrence, distant metastasis, overall survival, and disease-free survival between both groups. Compared with the abdominoperineal resection group, the conformal sphincter preservation operation group had shorter operative time and shorter postoperative hospital stay. No significant differences were identified in local recurrence, distant metastasis, overall survival, and disease-free survival.

conclusionConformal sphincter preservation operation is oncologically safe compared to APR and LAR, and has similar functional findings to LAR. Studies comparing CSPO with intersphincteric resection should be performed.

Indexed as

NeoplasmsProctectomyAnal CanalCohort StudiesHumansPropensity ScoreRetrospective StudiesAbdominoperineal resectionConformal sphincter preservationLow anterior resectionPropensity score matchingVery low rectal cancer

Identifiers

PMID37222797
OpenAlexW4377940851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.