Evidence map›Paper›PMID 37222701›Full record

ArticleeLife2023

Gene editing and scalable functional genomic screening in

Markus Engstler, Tom Beneke

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. CRISPR-Cas13b mediated gene knockdowns in Leishmania infantum.International journal for parasitology. Drugs and drug resistance · 2025
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Recent advances in the genetic engineering of theIranian journal of basic medical sciences · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Markus EngstlerDepartment of Cell and Developmental Biology, Biocentre, University of Würzburg, Wuerzburg, Germany.
Tom BenekeDepartment of Cell and Developmental Biology, Biocentre, University of Würzburg, Wuerzburg, Germany.ORCID 0000-0001-9117-2649
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CRISPR/Cas9 gene editing has revolutionised loss-of-function experiments in

Indexed as

LeishmaniaCRISPR-Cas SystemsCytosineGene EditingGenomicsCytosineCRISPR/Cas9cytosine base editorgeneticsgenomicsinfectious diseaseLeishBASEeditLeishmanialoss-of-function screeningmicrobiology

Identifiers

PMID37222701
PMCPMC10208639
OpenAlexW4377939153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.