Evidence map›Paper›PMID 37222630›Full record

ArticleJournal of clinical microbiology2023

Refining Timely Diagnosis of Early Syphilis by Using Treponema pallidum PCR or IgM Immunoblotting Next to Conventional Serology for Syphilis.

Jacky Flipse, Anne-Marie Niekamp, Anne Dirks, Nicole H T M Dukers-Muijrers, Christian J P A Hoebe, Petra Wolffs, Inge H M van Loo

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Update on syphilis diagnostics.Current opinion in infectious diseases · 2025
    Review
  6. An Update on the Status of Direct Testing forJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2024
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jacky Flipse *Department of Medical Microbiology, Infectious Diseases, and Infection Prevention, Maastricht University Medical Centre, Care and Public Health Research Institute, Maastricht, the Netherlands.ORCID 0000-0002-2195-5282
Anne-Marie Niekamp *Department of Sexual Health, Infectious Diseases, and Environmental Health, Living Lab Public Health, Public Health Service South Limburg, Heerlen, the Netherlands.
Anne DirksDepartment of Medical Microbiology, Infectious Diseases, and Infection Prevention, Maastricht University Medical Centre, Care and Public Health Research Institute, Maastricht, the Netherlands.
Nicole H T M Dukers-MuijrersDepartment of Sexual Health, Infectious Diseases, and Environmental Health, Living Lab Public Health, Public Health Service South Limburg, Heerlen, the Netherlands.
Christian J P A HoebeDepartment of Medical Microbiology, Infectious Diseases, and Infection Prevention, Maastricht University Medical Centre, Care and Public Health Research Institute, Maastricht, the Netherlands.
Petra WolffsDepartment of Medical Microbiology, Infectious Diseases, and Infection Prevention, Maastricht University Medical Centre, Care and Public Health Research Institute, Maastricht, the Netherlands.ORCID 0000-0002-5326-3985
Inge H M van LooDepartment of Medical Microbiology, Infectious Diseases, and Infection Prevention, Maastricht University Medical Centre, Care and Public Health Research Institute, Maastricht, the Netherlands.
Maastricht University Medical Centre · NLMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treponema pallidum subsp.

Indexed as

Diagnostic Tests, RoutineImmunoglobulin MSyphilisHumansImmunoblottingPolymerase Chain ReactionSensitivity and SpecificitySerologic TestsTreponema pallidumImmunoglobulin MIgM immunoblotPCRpublic healthserologySTI clinicsyphilisTreponema pallidum

Identifiers

PMID37222630
PMCPMC10281170
OpenAlexW4377939159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.