Evidence map›Paper›PMID 37222047›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Modular Hydrogel Vaccine for Programmable and Coordinate Elicitation of Cancer Immunotherapy.

Panpan Ji, Wenqi Sun, Siyan Zhang, Yuqi Xing, Chen Wang, Mengying Wei, Qiuyun Li, Gang Ji, Guodong Yang

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Panpan JiDepartment of Digestive Surgery, Xijing Hospital, Fourth Military Medical University, Shaanxi, 710032, China.ORCID 0000-0002-7786-6844
Wenqi SunDepartment of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Shaanxi, 710038, China.
Siyan ZhangDepartment of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Shaanxi, 710038, China.
Yuqi XingThe State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Shaanxi, 710032, China.
Chen WangDepartment of Ultrasound Diagnostics, Tangdu Hospital, Fourth Military Medical University, Shaanxi, 710038, China.
Mengying WeiThe State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Shaanxi, 710032, China.
Qiuyun LiDepartment of Breast Surgery, The Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China.
Gang JiDepartment of Digestive Surgery, Xijing Hospital, Fourth Military Medical University, Shaanxi, 710032, China.
Guodong YangThe State Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Shaanxi, 710032, China.
Air Force Medical University · CNTang Du Hospital · CNXijing Hospital · CNTumor Hospital of Guangxi Medical University · CN

Funding

National Natural Science Foundation of China 82260479State Laboratory of Cancer Biology CBSKL2019ZZ14State Laboratory of Cancer Biology CBSKL2022ZZ17
6 · The paper itself

Abstract

Immunotherapy holds great promise for the treatment of malignant cancer. However, the lack of sufficient tumor neoantigens and incomplete dendritic cell (DC) maturation compromise the efficacy of immunotherapy. Here, a modular hydrogel-based vaccine capable of eliciting a powerful and sustained immune response is developed. Briefly, CCL21a and Exo

Indexed as

NeoplasmsVaccinesGranulocyte-Macrophage Colony-Stimulating FactorHydrogelsImmunotherapyGranulocyte-Macrophage Colony-Stimulating FactorHydrogelsVaccinesantigen presentationcancer immunotherapyexosomeshydrogelprogrammed releasevaccine

Identifiers

PMID37222047
PMCPMC10401092
OpenAlexW4377940223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.